Royer Michael C, Sperling Leonard C
Armed Forces Institute of Pathology, Washington, DC, USA.
J Cutan Pathol. 2006 Sep;33 Suppl 2:63-4. doi: 10.1111/j.1600-0560.2006.00526.x.
A 43-year-old male presented with the clinical findings of patchy alopecia that contained persistent hair and re-growth of hairs of various lengths, consistent with trichotillomania. A biopsy was performed to confirm the diagnosis..
Histologic evaluation revealed findings consistent with trichotillomania, including trichomalacia. Several hair shafts also showed a vertically oriented split, which contained proteinaceous material and erythrocytes. Morphologically, these were reminiscent of a hamburger within a bun.
The unusual finding reported in this case has not been previously reported. The "hamburger bun sign" provides an additional clue to traumatic injury in the evaluation of biopsies for trichotillomania.
一名43岁男性出现斑片状脱发的临床表现，脱发区有残留毛发及不同长度毛发的再生，符合拔毛癖。进行了活检以确诊。
组织学评估显示符合拔毛癖的表现，包括毛发软化。几根毛干还显示出垂直方向的裂隙，其中含有蛋白质物质和红细胞。形态上，这些类似于夹在面包中的汉堡。
该病例中报告的这一不寻常发现此前未见报道。“汉堡面包征”为拔毛癖活检评估中的创伤性损伤提供了额外线索。
