Hamm H, Traupe H
Department of Dermatology, University of Münster, FRG.
J Am Acad Dermatol. 1989 Feb;20(2 Pt 1):242-8. doi: 10.1016/s0190-9622(89)70029-3.
We report two unrelated boys aged 4 and 9 years who had the recently delineated phenomenon of easily pluckable hair. Hair tufts could be pulled out without effort and without pain. Alopecia without any sign of scalp inflammation or scarring was noted. In the older child spontaneous remission occurred within 3 months, whereas the condition remained active in the younger boy for a follow-up period of 1 year. Trichograms from clinically involved and uninvolved areas disclosed a striking predominance of anagen hairs (98% to 100%) and complete absence of telogen hairs. A loss of the normal round or oval configuration of many hair shafts could be well visualized by the shrinking tube technique. Horizontal and transverse sections of scalp obtained for biopsy revealed marked cleft formations between hair shafts and regressively altered inner root sheaths. We suggest the name loose anagen hair of childhood for this newly described disease.
我们报告了两名年龄分别为4岁和9岁的无血缘关系男孩，他们出现了最近才明确描述的毛发易拔除现象。发簇可以轻松拔出，且无痛感。观察到脱发但没有任何头皮炎症或瘢痕的迹象。年龄较大的儿童在3个月内自发缓解，而年龄较小的男孩在1年的随访期内病情仍处于活动状态。对临床受累和未受累区域进行的毛发检查显示，生长期毛发显著占优势（98%至100%），且完全没有休止期毛发。通过收缩管技术可以清楚地看到许多毛干正常的圆形或椭圆形形态消失。为活检获取的头皮水平和横切面显示，毛干与退行性改变的内根鞘之间有明显的裂隙形成。我们建议将这种新描述的疾病命名为儿童松动生长期毛发。
