Maple-Brown L J, Brimblecombe J, Chisholm D, O'Dea K
Menzies School of Health Research, P.O. Box 41096, Casuarina, NT 0811, Australia.
Diabetes Res Clin Pract. 2004 May;64(2):77-83. doi: 10.1016/j.diabres.2003.10.008.
Prevalence of complications of type 2 diabetes in a remote Australian Indigenous community was measured as part of a population survey of risk factors for diabetes and cardiovascular disease. Information was obtained from history, clinical examination, blood sample and medical records. Forty-three diabetic participants (six newly diagnosed) were assessed from a sample of 339 (12% diabetes prevalence); mean age 50 (range 31-67), duration of diabetes 5.6 (0-15) years, 40% male. Risk factors/complications: 70% with >/= 25, 50% cigarette smokers, HbA1c 8.5 (S.D. 2.9)%, cholesterol 4.8 (0.8)mmol/l, triglycerides 2.7 (1.6)mmol/l, HDL 0.83 (0.2)mmol/l; 60% had albuminuria (micro 38%, macro 22%), 47% were hypertensive, 7% (n = 2) had retinopathy, 24% had peripheral neuropathy, none had peripheral vascular disease, 14% had documented coronary vascular and one participant cerebrovascular disease. Of 37 with previously diagnosed diabetes: 43% were on aspirin, 65% on metformin, 80% with albuminuria on ACE inhibitors. Four additional diabetic participants (not studied) were receiving renal dialysis elsewhere. The results demonstrate on the one hand, very high indices of cardiovascular risk (smoking, hypertension, dyslipidaemia and albuminuria) and on the other, good quality primary health care providing good detection and follow up management of type 2 diabetic patients.
作为糖尿病和心血管疾病危险因素人群调查的一部分,对澳大利亚一个偏远土著社区2型糖尿病并发症的患病率进行了测量。通过病史、临床检查、血样和医疗记录获取信息。从339名样本中评估了43名糖尿病参与者(6名新诊断患者);糖尿病患病率为12%;平均年龄50岁(范围31 - 67岁),糖尿病病程5.6年(0 - 15年),男性占40%。危险因素/并发症:70%的人年龄≥25岁,50%为吸烟者,糖化血红蛋白(HbA1c)为8.5%(标准差2.9),胆固醇4.8(0.8)mmol/l,甘油三酯2.7(1.6)mmol/l,高密度脂蛋白(HDL)0.83(0.2)mmol/l;60%有蛋白尿(微量蛋白尿占38%,大量蛋白尿占22%),47%患有高血压,7%(n = 2)有视网膜病变,24%有周围神经病变,无人有外周血管疾病,14%有记录的冠状动脉血管疾病,1名参与者有脑血管疾病。在37名先前诊断为糖尿病的患者中:43%服用阿司匹林,65%服用二甲双胍,80%有蛋白尿的患者服用血管紧张素转换酶(ACE)抑制剂。另外4名糖尿病参与者(未纳入研究)在其他地方接受肾透析。结果一方面显示出心血管风险指标非常高(吸烟、高血压、血脂异常和蛋白尿),另一方面显示出优质的初级卫生保健能够对2型糖尿病患者进行良好的检测和后续管理。