Kiecolt-Glaser J K, Glaser R
Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210.
J Consult Clin Psychol. 1992 Aug;60(4):569-75. doi: 10.1037//0022-006x.60.4.569.
There is ample evidence from human and animal studies demonstrating the downward modulation of immune function concomitant with a variety of stressors. As a consequence, the possible enhancement of immune function by behavioral strategies has generated considerable interest. Researchers have used a number of diverse strategies to modulate immune function, including relaxation, hypnosis, exercise, classical conditioning, self-disclosure, exposure to a phobic stressor to enhance perceived coping self-efficacy, and cognitive-behavioral interventions, and these interventions have generally produced positive changes. Although it is not yet clear to what extent these positive immunological changes translate into any concrete improvements in relevant aspects of health, that is, alterations in the incidence, severity, or duration of infectious or malignant disease, the preliminary evidence is promising.
来自人类和动物研究的大量证据表明，免疫功能的下调与多种应激源同时出现。因此，行为策略对免疫功能的潜在增强作用引起了广泛关注。研究人员采用了多种不同策略来调节免疫功能，包括放松、催眠、运动、经典条件反射、自我表露、接触恐惧应激源以增强自我效能感，以及认知行为干预，这些干预通常都产生了积极变化。尽管目前尚不清楚这些积极的免疫学变化在多大程度上转化为健康相关方面的具体改善，即传染病或恶性疾病的发病率、严重程度或持续时间的改变，但初步证据很有前景。
