Swartz Holly A, Frank Ellen, Shear M Katherine, Thase Michael E, Fleming M A Dana, Scott John
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
Psychiatr Serv. 2004 Apr;55(4):448-50. doi: 10.1176/appi.ps.55.4.448.
A matched-case-control study compared eight-week outcomes between a group of 16 depressed women who received brief (eight-session) interpersonal psychotherapy and a group of 16 who received a selective serotonin reuptake inhibitor (sertraline). Women who met DSM-IV criteria for major depression and who had a score above 15 on the Hamilton Rating Scale for Depression were treated openly with brief interpersonal psychotherapy and were matched on key variables with women being treated with sertraline. Linear mixed-effects regression models were used to compare groups on measures of symptoms and functioning during eight weeks of treatment. Both groups improved significantly over time, with large effect sizes. However, contrary to expectations, the women who received psychotherapy improved more quickly than those who received sertraline.
一项配对病例对照研究比较了一组16名接受简短（八节）人际心理治疗的抑郁女性与一组16名接受选择性5-羟色胺再摄取抑制剂（舍曲林）治疗的女性在八周时的结果。符合《精神疾病诊断与统计手册》第四版（DSM-IV）重度抑郁症标准且汉密尔顿抑郁量表评分高于15分的女性，接受简短人际心理治疗的公开治疗，并在关键变量上与接受舍曲林治疗的女性进行匹配。使用线性混合效应回归模型比较两组在八周治疗期间的症状和功能指标。随着时间的推移，两组均有显著改善，效应量较大。然而，与预期相反，接受心理治疗的女性比接受舍曲林治疗的女性改善得更快。
