Gajdosova J, Reichrtova E
Institute of Preventive and Clinical Medicine, Limbova 14, Bratislava, Slovak Republic.
Anal Bioanal Chem. 1996 Mar;354(5-6):641-2. doi: 10.1007/s0021663540641.
The toxicity of inorganic mercury, nickel, chromium and cadmium on the unicellular photosynthetic flagellate Euglena gracilis, strain Z (E.g.) has been tested. Under the conditions used each metal impaired the growth rate of E.g., and had a very strong effect on cell motility. The degree of cytotoxicity and motility decreased from mercury iodide to cadmium chloride to cadmium nitrate to potassium dichromate to nickel sulfate. No mutagenic effects of the metals investigated have been observed. Adverse effects of metal compounds can be tested on the eukaryotic species of Euglena gracilis used as an intermediate model system between bacterial and animal model.
已对无机汞、镍、铬和镉对单细胞光合鞭毛虫纤细裸藻Z株(E.g.)的毒性进行了测试。在所使用的条件下,每种金属都损害了E.g.的生长速率,并对细胞运动性有非常强烈的影响。细胞毒性和运动性的程度从碘化汞到氯化镉、到硝酸镉、到重铬酸钾、再到硫酸镍依次降低。未观察到所研究金属的诱变效应。金属化合物的不良影响可以在用作细菌和动物模型之间的中间模型系统的真核生物纤细裸藻上进行测试。