Bhatnagar Parul, Bhatnagar Aseem, Kishan Sawroop, Bal C S, Saran Ravinder Kumar, Sinha Sanjeev, Kashyap Ravi
Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
Clin Nucl Med. 2004 May;29(5):303-5. doi: 10.1097/01.rlu.0000122802.64681.2d.
Mixed medullary-follicular thyroid carcinoma (MMFTC) is a rare tumor with a metastatic behavior that has not been fully appreciated. Scintigraphy and radioiodine entrapment propensity of its metastases remains largely undescribed. The authors present a case of MMFTC with widespread bone and soft-tissue metastases, where every known site of metastases concentrated radioiodine intensely. The patient responded well to radioiodine therapy. The report suggests that the tumor may have a propensity to metastasize to the skeleton, and the metastases retain the ability to accumulate radioiodine.