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甲状腺转移性岛状癌的放射性核素对比成像:锝-99m-(V)二巯基丁二酸的价值

Comparative radionuclide imaging of metastatic insular carcinoma of the thyroid: value of technetium-99m-(V)DMSA.

作者信息

Yen T C, King K L, Yang A H, Liu R S, Yeh S H

机构信息

Department of Nuclear Medicine, Veterans General Hospital, Taipei, Taiwan.

出版信息

J Nucl Med. 1996 Jan;37(1):78-80.

PMID:8544007
Abstract

We report a case of metastatic insular carcinoma of the thyroid evaluated with 201TI, 99mTc-MIBI, 99mTc-(V)DMSA, 99mTc-MDP and 131I whole-body scans, which were obtained after total thyroidectomy. For the majority of lesions detected in the skeleton and soft tissue, 131I images were generally available, although most were visualized easier with 99mTc-(V)DMSA. Technetium-99m-MDP images were considered better than 99mTc-(V)DMSA images in showing bone lesions but not soft-tissue lesions. Both 201TI and 99mTc-MIBI scans provided sufficient advantage to exhibit neck and mediastinal metastases, but they did not surpass 99mTc-(V)DMSA in detecting abdominal or bony lesions. In this patient with various metastases from insular carcinoma of the thyroid, 99mTc-(V)DMSA seemed to be the tracer of choice for whole-body imaging.

摘要

我们报告一例甲状腺岛状癌转移患者,在全甲状腺切除术后进行了铊-201、锝-99m甲氧基异丁基异腈、锝-99m(V)二巯基丁二酸、锝-99m亚甲基二膦酸盐和碘-131全身扫描评估。对于在骨骼和软组织中检测到的大多数病变,碘-131图像通常是可用的,尽管大多数病变用锝-99m(V)二巯基丁二酸更容易显示。锝-99m亚甲基二膦酸盐图像在显示骨病变方面被认为优于锝-99m(V)二巯基丁二酸图像,但在显示软组织病变方面则不然。铊-201和锝-99m甲氧基异丁基异腈扫描在显示颈部和纵隔转移方面都具有足够的优势,但在检测腹部或骨病变方面它们没有超过锝-99m(V)二巯基丁二酸。在这名患有甲状腺岛状癌多处转移的患者中,锝-99m(V)二巯基丁二酸似乎是全身成像的首选示踪剂。

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Comparative radionuclide imaging of metastatic insular carcinoma of the thyroid: value of technetium-99m-(V)DMSA.甲状腺转移性岛状癌的放射性核素对比成像:锝-99m-(V)二巯基丁二酸的价值
J Nucl Med. 1996 Jan;37(1):78-80.
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