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[骨溶解与稳定的全髋关节置换术相关时是否无症状?]

[Is osteolysis associated with a stable total hip replacement asymptomatic?].

作者信息

Gallo J, Kamínek P, Zapletalová J, Cechová I, Spicka J, Ditmar R

机构信息

Ortopedická klinika LF UP a FN Olomouc.

出版信息

Acta Chir Orthop Traumatol Cech. 2004;71(1):20-5.

Abstract

PURPOSE OF THE STUDY

It has been reported that periprosthetic osteolysis in a stable cementless total hip prosthesis is often free from symptoms. The aim of this study is to check this assumption and provide details on the clinical presentation of this troublesome and worrying complication of hip arthroplasty.

MATERIAL

Between March 1999 and June 2002, 76 hips in 72 patients underwent revision arthroplasty for periprosthetic osteolysis associated with stable ABG I prostheses. This patient group included 53 females and 19 males. The average age at the time of revision was 49 years (range, 32 to 63). The average time between the primary and revision surgery was 54.6 months (range, 23 to 85). The average cup size was 49.7 mm (range, 44 to 60), the modular 28-mm CoCr head was used in 69 hips, 28-mm ceramic head in six hips, and 22-mm CoCr head in one patient.

METHODS

The following characteristics were recorded: gender, age, type of patient, height, weight, symptoms, diagnosis, ERS, CRP, Harris hip score, cup size, abduction angle and extent of bony defects. The data of symptomatic and asymptomatic patients were compared by parametric or non-parametric tests.

RESULTS

Before revision, 61 hips (80%) were symptomatic. The patients complained of pain or signs of instability or both, and these complaints were taken as indications for revision surgery. The remaining 15 hips (20%) were asymptomatic. The average period from the primary surgery to the appearance of the first symptoms was 43 months (range, 5 to 80). The average Harris hip score before revision was 68 points (range, 37 to 90) and 82 points (range, 10 to 98) in the symptomatic and asymptomatic patients, respectively (p = 0.002). There were no other significant differences between these patients.

DISCUSSION

The results of our study are in agreement with the findings of Hozack et al., but not with those of Maloney et al. and others who have reported that the progression of osteolysis developing in association with hip arthroplasty can be without symptoms.

CONCLUSIONS

Osteolysis developing around a stable cementless hip prosthesis is generally symptomatic, with pain being the most frequent symptom. Even without a periprosthetic fracture, osteolysis may seriously impair the function of a joint and comfort of the patient. Since symptomatic patients are likely to see their attending physicians, it is emphasized that attention should also be paid to asymptomatic patients who have prostheses with unsuitable designs or pairings.

摘要

研究目的

据报道,稳定的非骨水泥型全髋关节假体周围骨溶解通常没有症状。本研究的目的是验证这一假设,并详细阐述髋关节置换术中这种麻烦且令人担忧的并发症的临床表现。

材料

1999年3月至2002年6月期间,72例患者的76髋因与稳定的ABG I型假体相关的假体周围骨溶解接受了翻修关节成形术。该患者组包括53名女性和19名男性。翻修时的平均年龄为49岁(范围32至63岁)。初次手术与翻修手术之间的平均时间为54.6个月(范围23至85个月)。平均髋臼杯尺寸为49.7毫米(范围44至60毫米),69髋使用了模块化28毫米钴铬合金股骨头,6髋使用了28毫米陶瓷股骨头,1例患者使用了22毫米钴铬合金股骨头。

方法

记录以下特征:性别、年龄、患者类型、身高、体重、症状、诊断、红细胞沉降率(ERS)、C反应蛋白(CRP)、Harris髋关节评分、髋臼杯尺寸、外展角度和骨缺损范围。有症状和无症状患者的数据通过参数检验或非参数检验进行比较。

结果

翻修前,61髋(80%)有症状。患者主诉疼痛或不稳定迹象或两者皆有,这些主诉被视为翻修手术的指征。其余15髋(20%)无症状。从初次手术到出现首个症状的平均时间为43个月(范围5至80个月)。有症状和无症状患者翻修前的平均Harris髋关节评分分别为68分(范围37至90分)和82分(范围10至98分)(p = 0.002)。这些患者之间没有其他显著差异。

讨论

我们的研究结果与霍扎克等人的研究结果一致,但与马洛尼等人以及其他报告髋关节置换术中发生的骨溶解进展可能无症状的研究结果不一致。

结论

稳定的非骨水泥型髋关节假体周围发生的骨溶解通常有症状,疼痛是最常见的症状。即使没有假体周围骨折,骨溶解也可能严重损害关节功能和患者舒适度。由于有症状的患者可能会去看他们的主治医生,因此强调对于假体设计或配对不合适的无症状患者也应予以关注。

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