Richardson N E, Meakin B J
J Pharm Pharmacol. 1977 Feb;29(2):86-8. doi: 10.1111/j.2042-7158.1977.tb11251.x.
The influence of temperature on the sorption of benzocaine by nylon 6 powder from aqueous cosolvents has been assessed. At about 30 degrees discontinuities appear in the Van't Hoff plots for sorption from water and aqueous PEG 400, which may be attributed to transitional changes in the polymer structure. No such discontinuities are apparent for sorption from aqueous ethanol over the temperature range 15-60 degrees, which is indicative of plasticizaton by this cosolvent.
已评估温度对尼龙6粉末从水性共溶剂中吸附苯佐卡因的影响。在约30摄氏度时,从水和聚乙二醇400水溶液中吸附的范特霍夫图出现不连续性,这可能归因于聚合物结构的转变。在15至60摄氏度的温度范围内,从乙醇水溶液中吸附时未出现此类不连续性,这表明该共溶剂具有增塑作用。