助溶剂和底物取代基对聚酰胺吸附苯甲酸衍生物的影响。

The influence of cosolvents and substrate substituents on the sorption of benzoic acid derivatives by polyamides.

作者信息

Richardson N E, Meakin B J

出版信息

J Pharm Pharmacol. 1975 Mar;27(3):145-51. doi: 10.1111/j.2042-7158.1975.tb09428.x.

DOI:10.1111/j.2042-7158.1975.tb09428.x

Abstract

The sorption of some substituted benzoic acid derivatives by polyamides (nylons) from aqueous solution has been examined and the influence of their nature together with those of the cosolvent and polymer have been assessed. In all cases the sorption isotherms were linear and could be expressed by a simple distribution law, enabling the influence of cosolvent concentration to be predicted. The sorption of a series of p-substituted benzoic acids and some of their esters is related to their solubility except where the p-substituent is capable of hydrogen-bonding with the polymer. The extent of the interaction is also dependent upon the amide frequency of the polymer.

摘要

研究了聚酰胺（尼龙）从水溶液中对一些取代苯甲酸衍生物的吸附作用，并评估了它们的性质以及助溶剂和聚合物的性质的影响。在所有情况下，吸附等温线都是线性的，可以用简单的分配定律表示，从而能够预测助溶剂浓度的影响。一系列对取代苯甲酸及其某些酯的吸附与它们的溶解度有关，除非对取代基能够与聚合物形成氢键。相互作用的程度还取决于聚合物的酰胺频率。