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一种微型金属氧化物半导体场效应晶体管(micro-MOSFET)的特性与性能:一种用于图像引导放射治疗的“可成像”剂量计。

Characteristics and performance of a micro-MOSFET: an "imageable" dosimeter for image-guided radiotherapy.

作者信息

Rowbottoma Carl G, Jaffray David A

机构信息

Department of Radiation Oncology, William Beaumont Hospital, 3601 W 13 Mile Road, Royal Oak, Michigan 48073, USA.

出版信息

Med Phys. 2004 Mar;31(3):609-15. doi: 10.1118/1.1649532.

Abstract

The performance and characteristics of a miniature metal oxide semiconductor field effect transistor (micro-MOSFET) detector was investigated for its potential application to integral system tests for image-guided radiotherapy. In particular, the position of peak response to a slit of radiation was determined for the three principal axes to define the co-ordinates for the center of the active volume of the detector. This was compared to the radiographically determined center of the micro-MOSFET visible using cone-beam CT. Additionally, the angular sensitivity of the micro-MOSFET was measured. The micro-MOSFETs are clearly visible on the cone-beam CT images, and produce no artifacts. The center of the active volume of the micro-MOSFET aligned with the center of the visible micro-MOSFET on the cone-beam CT images for the x and y axes to within 0.20 mm and 0.15 mm, respectively. In z, the long axis of the detector, the peak response was found to be 0.79 mm from the tip of the visible micro-MOSFET. Repeat experiments verified that the position of the peak response of the micro-MOSFET was reproducible. The micro-MOSFET response for 360 degrees of rotation in the axial plane to the micro-MOSFET was +/-2%, consistent with values quoted by the manufacturer. The location of the active volume of the micro-MOSFETs under investigation can be determined from the centroid of the visible micro-MOSFET on cone-beam CT images. The CT centroid position corresponds closely to the center of the detector response to radiation. The ability to use the cone-beam CT to locate the active volume to within 0.20 mm allows their use in an integral system test for the imaging of and dose delivery to a phantom containing an array of micro-MOSFETs. The small angular sensitivity allows the investigation of noncoplanar beams.

摘要

研究了一种微型金属氧化物半导体场效应晶体管(micro-MOSFET)探测器的性能和特性,以探讨其在图像引导放射治疗整体系统测试中的潜在应用。具体而言,确定了探测器对辐射狭缝的峰值响应位置在三个主轴上的情况,以定义探测器有效体积中心的坐标。将此与通过锥束CT确定的可见micro-MOSFET的中心进行比较。此外,还测量了micro-MOSFET的角度灵敏度。在锥束CT图像上,micro-MOSFET清晰可见,且不产生伪影。在x轴和y轴上,micro-MOSFET有效体积的中心与锥束CT图像上可见的micro-MOSFET的中心对齐,偏差分别在0.20 mm和0.15 mm以内。在探测器的长轴z方向上,发现峰值响应距离可见micro-MOSFET的尖端为0.79 mm。重复实验证实了micro-MOSFET峰值响应的位置具有可重复性。在轴向平面内,micro-MOSFET旋转360度时的响应为+/-2%,与制造商提供的值一致。通过锥束CT图像上可见micro-MOSFET的质心,可以确定所研究的micro-MOSFET的有效体积位置。CT质心位置与探测器对辐射的响应中心密切对应。利用锥束CT将有效体积定位在0.20 mm以内的能力,使得它们可用于对包含一系列micro-MOSFET的模体进行成像和剂量输送的整体系统测试。较小的角度灵敏度使得能够研究非共面射束。

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