Nylen Eric S, Muller Beat
Department of Medicine, Section of Endocrinology, George Washington University School of Medicine, and Veterans Affairs Medical Center, 50 Irving St, NW, Rm GE246, Washington, DC 20422, USA.
J Intensive Care Med. 2004 Mar-Apr;19(2):67-82. doi: 10.1177/0885066603259551.
The homeostatic corrections that have emerged in the course of human evolution to cope with catastrophic events involve a complex multisystem endeavor, of which the endocrine contribution is an integral component. Although the repertoire of endocrine changes has been probed in some detail, discerning the vulnerabilities and failure of this system is far more challenging. The ensuing endocrine topics illustrate some of the current issues reflecting attempts to gain an improved insight and clinical outcome for critical illness.
在人类进化过程中出现的、用于应对灾难性事件的稳态校正涉及一项复杂的多系统活动，其中内分泌的作用是不可或缺的一部分。尽管已经对内分泌变化的全部内容进行了一定程度的探究，但识别该系统的脆弱性和功能衰竭要困难得多。接下来的内分泌相关主题阐述了一些当前的问题，这些问题反映了为改善危重病的认知和临床结局所做的努力。
