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滑膜骨软骨瘤病。简要综述。

Synovial osteochondromatosis. A brief review.

作者信息

Valmassy R, Ferguson H

机构信息

Center for Sports Medicine, St Francis Memorial Hospital, San Francisco, CA.

出版信息

J Am Podiatr Med Assoc. 1992 Aug;82(8):427-31. doi: 10.7547/87507315-82-8-427.

DOI:10.7547/87507315-82-8-427
PMID:1507082
Abstract

An unusual clinical finding is presented with a brief review of the literature. Synovial osteochondromatosis is typically a benign process involving metaplasia of the synovial intima and the formation of cartilaginous nodules that may eventually become ossified. Synovial osteochondromatosis should always be considered as a differential diagnosis whenever a patient presents with pain, swelling, and loss of function at or around a joint. Chondrosarcoma has been misdiagnosed, leading to radical and unnecessary amputation, because synovial osteochondromatosis has not been considered. Alternatively, synovial osteochondromatosis may degenerate to or be associated with a malignant process. When radiographs or more sophisticated investigative procedures, such as magnetic resonance imaging, fail to provide a conclusive answer, histologic findings provide the definitive diagnosis.

摘要

本文呈现了一项不同寻常的临床发现,并对相关文献进行了简要回顾。滑膜骨软骨瘤病通常是一种良性病变,涉及滑膜内膜化生以及软骨结节形成,这些结节最终可能会骨化。每当患者出现关节处或关节周围疼痛、肿胀及功能丧失时,滑膜骨软骨瘤病都应始终被视为鉴别诊断的对象。由于未考虑到滑膜骨软骨瘤病,软骨肉瘤曾被误诊,导致了根治性且不必要的截肢。另外,滑膜骨软骨瘤病可能会恶变为恶性病变或与恶性病变相关。当X线片或更复杂的检查手段,如磁共振成像,无法给出确定性答案时,组织学检查结果可提供明确诊断。

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