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滑膜骨软骨瘤病酷似青少年特发性关节炎:基于病例的综述。

Synovial osteochondromatosis mimicking juvenile idiopathic arthritis in an adolescent: a case-based review.

机构信息

Division of Rheumatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Clin Rheumatol. 2022 Aug;41(8):2571-2580. doi: 10.1007/s10067-022-06224-w. Epub 2022 May 31.

Abstract

Synovial osteochondromatosis is an extremely rare benign condition in children and adolescents that have joint pain as a presenting manifestation. It is usually monoarticular with the knee as the most common affected joint. In this article, we describe the case of a female adolescent suffering from debilitating chronic right knee pain initially mimicking juvenile idiopathic arthritis, who was subsequently diagnosed with primary synovial osteochondromatosis. We present a review of synovial osteochondromatosis focusing on the clinical manifestations, radiographic features, histopathologic findings, and treatment, with a summarized review of pediatric patients with initial musculoskeletal presentations who were ultimately diagnosed as synovial osteochondromatosis. Although synovial osteochondromatosis is rare in children and adolescents, this condition should be included in the differential diagnosis of joint pain and may mimic juvenile idiopathic arthritis. Appropriate diagnostic radiography, including both plain radiography and magnetic resonance imaging, is necessary to accurately diagnose this condition. We also emphasize the importance of a multidisciplinary team approach to managing patients with synovial osteochondromatosis.

摘要

滑膜骨软骨瘤病是一种极为罕见的儿童和青少年良性疾病,以关节痛为主要表现。它通常是单关节病变,最常见的受累关节是膝关节。本文描述了一例女性青少年患有进行性慢性右膝关节疼痛,最初类似于幼年特发性关节炎,随后被诊断为原发性滑膜骨软骨瘤病。我们回顾了滑膜骨软骨瘤病,重点介绍了临床表现、影像学特征、组织病理学发现和治疗,并总结了最初表现为肌肉骨骼系统的儿科患者,最终被诊断为滑膜骨软骨瘤病。尽管滑膜骨软骨瘤病在儿童和青少年中较为罕见,但这种疾病应纳入关节痛的鉴别诊断,可能与幼年特发性关节炎相混淆。适当的诊断性影像学检查,包括平片和磁共振成像,对于准确诊断这种疾病是必要的。我们还强调了多学科团队方法在管理滑膜骨软骨瘤病患者中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35f1/9154203/76133fbd8d68/10067_2022_6224_Fig1_HTML.jpg

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