Manfredini D, Tognini F, Melchiorre D, Zampa V, Bosco M
Section of Prosthetic Dentistry, Department of Neuroscience, University of Pisa, Italy.
Dentomaxillofac Radiol. 2003 Nov;32(6):359-64. doi: 10.1259/dmfr/25091144.
The aim of this study was to evaluate whether an increased capsular width evidenced by ultrasound (US) could be an indirect marker of temporomandibular joint (TMJ) effusion.
138 TMJs were evaluated by US and magnetic resonance imaging (MRI) by two blinded calibrated investigators. US measures of capsular width (in mm) and MRI diagnosis of TMJ effusion (presence/absence) were used to perform a receiver operating characteristic (ROC) curve analysis in order to assess the most accurate cut-off value of capsular width that was able to discriminate between joints with and without MRI effusion.
Diagnostic accuracy of US to detect MRI-depicted TMJ effusion was good (area under the ROC curve=0.817). US sensitivity was high for values below the cut-off value of 1.950 mm (true positive rate (TPR)=83.9%; false positive rate (FPR)=26.3%), while specificity was high for values above the cut-off value of 2.150 mm (TPR=71.0%; FPR=11.8%).
Analysis of ROC curve appears to reveal that the critical area is around the 2 mm value for TMJ capsular width. These findings need to be refined by further studies assessing the smallest detectable difference in capsular width, with attention to reliability of interobserver observations.
本研究旨在评估超声(US)显示的关节囊宽度增加是否可能是颞下颌关节(TMJ)积液的间接标志物。
由两名经过校准的盲法研究者对138个颞下颌关节进行超声和磁共振成像(MRI)评估。采用超声测量关节囊宽度(以毫米为单位)和MRI诊断颞下颌关节积液(存在/不存在),进行受试者操作特征(ROC)曲线分析,以评估能够区分有和没有MRI积液的关节的关节囊宽度的最准确临界值。
超声检测MRI显示的颞下颌关节积液的诊断准确性良好(ROC曲线下面积=0.817)。对于低于1.950 mm临界值的值,超声敏感性较高(真阳性率(TPR)=83.9%;假阳性率(FPR)=26.3%),而对于高于2.150 mm临界值的值,特异性较高(TPR=71.0%;FPR=11.8%)。
ROC曲线分析似乎显示,颞下颌关节囊宽度的临界区域在2 mm左右。这些发现需要通过进一步研究来完善,评估关节囊宽度的最小可检测差异,并关注观察者间观察结果的可靠性。