• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Signaling the unfolded protein response from the endoplasmic reticulum.

作者信息

Zhang Kezhong, Kaufman Randal J

机构信息

Department of Biological Chemistry and Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.

出版信息

J Biol Chem. 2004 Jun 18;279(25):25935-8. doi: 10.1074/jbc.R400008200. Epub 2004 Apr 7.

DOI:10.1074/jbc.R400008200
PMID:15070890
Abstract
摘要

相似文献

1
Signaling the unfolded protein response from the endoplasmic reticulum.来自内质网的未折叠蛋白反应信号传导。
J Biol Chem. 2004 Jun 18;279(25):25935-8. doi: 10.1074/jbc.R400008200. Epub 2004 Apr 7.
2
Orchestrating the unfolded protein response in health and disease.调控健康与疾病中的未折叠蛋白反应。
J Clin Invest. 2002 Nov;110(10):1389-98. doi: 10.1172/JCI16886.
3
The unfolded protein response.未折叠蛋白反应
J Cell Sci. 2003 May 15;116(Pt 10):1861-2. doi: 10.1242/jcs.00408.
4
Human cytomegalovirus infection activates and regulates the unfolded protein response.人巨细胞病毒感染激活并调节未折叠蛋白反应。
J Virol. 2005 Jun;79(11):6890-9. doi: 10.1128/JVI.79.11.6890-6899.2005.
5
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.热休克蛋白90通过稳定肌醇需求酶1α来调节未折叠蛋白反应。
Mol Cell Biol. 2002 Dec;22(24):8506-13. doi: 10.1128/MCB.22.24.8506-8513.2002.
6
[Stress signaling from the endoplasmic reticulum].[来自内质网的应激信号传导]
Tanpakushitsu Kakusan Koso. 2004 May;49(7 Suppl):1002-5.
7
How transmembrane proteins sense endoplasmic reticulum stress.跨膜蛋白如何感知内质网应激。
Antioxid Redox Signal. 2007 Dec;9(12):2295-303. doi: 10.1089/ars.2007.1819.
8
A time-dependent phase shift in the mammalian unfolded protein response.哺乳动物未折叠蛋白反应中的时间依赖性相移。
Dev Cell. 2003 Feb;4(2):265-71. doi: 10.1016/s1534-5807(03)00022-4.
9
Gene induction in response to unfolded protein in the endoplasmic reticulum is mediated through Ire1p kinase interaction with a transcriptional coactivator complex containing Ada5p.内质网中未折叠蛋白引发的基因诱导是通过Ire1p激酶与包含Ada5p的转录共激活因子复合物相互作用介导的。
Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4289-94. doi: 10.1073/pnas.94.9.4289.
10
Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts.ATF6和Ire1p-XBP1的未折叠蛋白反应(UPR)信号与靶转录本水平的不一致。
Biochem Biophys Res Commun. 2004 Apr 30;317(2):390-6. doi: 10.1016/j.bbrc.2004.03.058.

引用本文的文献

1
An adaptive peptide-binding site in ubiquitin receptor hRpn13 revealed by structural studies.结构研究揭示泛素受体hRpn13中的一个适应性肽结合位点。
Nat Commun. 2025 Jul 1;16(1):5669. doi: 10.1038/s41467-025-60843-w.
2
StarD5 Plays a Critical Role in the Hepatocyte ER Stress Survival Response.StarD5在肝细胞内质网应激存活反应中起关键作用。
Int J Mol Sci. 2025 Apr 27;26(9):4157. doi: 10.3390/ijms26094157.
3
p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy.p.Phe508del-囊性纤维化跨膜传导调节因子转运:从未折叠蛋白反应、泛素-蛋白酶体系统及自噬角度看蛋白质质量控制
Int J Mol Sci. 2025 Apr 11;26(8):3623. doi: 10.3390/ijms26083623.
4
Targeting fibroblast growth factor (FGF)-21: a promising strategy for metabolic dysfunction-associated steatotic liver disease treatment.靶向成纤维细胞生长因子(FGF)-21:一种治疗代谢功能障碍相关脂肪性肝病的有前景的策略。
Front Pharmacol. 2025 Apr 22;16:1510322. doi: 10.3389/fphar.2025.1510322. eCollection 2025.
5
Comparative evaluation of the modulatory role of 1,25-dihydroxy-vitamin D on endoplasmic reticulum stress-induced effects in 2D and 3D cultures of the intestinal porcine epithelial cell line IPEC-J2.1,25-二羟基维生素D对猪肠道上皮细胞系IPEC-J2二维和三维培养中内质网应激诱导效应的调节作用的比较评估
J Anim Sci Biotechnol. 2024 Nov 10;15(1):153. doi: 10.1186/s40104-024-01112-6.
6
Screening a neurotransmitter-receptor-related inhibitor library identifies clomipramine HCl as a potential antiviral compound against Japanese encephalitis virus.筛选一个神经递质-受体相关抑制剂文库,确定盐酸氯米帕明为一种针对日本脑炎病毒的潜在抗病毒化合物。
Infect Med (Beijing). 2024 Aug 13;3(3):100130. doi: 10.1016/j.imj.2024.100130. eCollection 2024 Sep.
7
Environmental PM-triggered stress responses in digestive diseases.环境颗粒物引发的消化系统疾病应激反应。
eGastroenterology. 2024 Apr;2(2). doi: 10.1136/egastro-2024-100063. Epub 2024 May 3.
8
The Inhibition of the Membrane-Bound Transcription Factor Site-1 Protease (MBTP1) Alleviates the p.Phe508del-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Defects in Cystic Fibrosis Cells.膜结合型转录因子位点 1 蛋白酶(MBTP1)的抑制减轻了囊性纤维化跨膜电导调节因子(CFTR)p.Phe508del 缺陷型囊性纤维化细胞的缺陷。
Cells. 2024 Jan 18;13(2):185. doi: 10.3390/cells13020185.
9
Soloxolone methyl induces apoptosis and oxidative/ER stress in breast cancer cells and target cancer stem cell population.甲基索罗索隆可诱导乳腺癌细胞凋亡以及氧化/内质网应激,并靶向癌症干细胞群体。
Turk J Biol. 2023 Jun 5;47(4):247-261. doi: 10.55730/1300-0152.2660. eCollection 2023.
10
Endoplasmic Reticulum Stress and Its Impact on Adipogenesis: Molecular Mechanisms Implicated.内质网应激及其对脂肪生成的影响:涉及的分子机制。
Nutrients. 2023 Dec 12;15(24):5082. doi: 10.3390/nu15245082.