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Orchestrating the unfolded protein response in health and disease.

作者信息

Kaufman Randal J

机构信息

Department of Biological Chemistry, Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor 48109-0650, USA.

出版信息

J Clin Invest. 2002 Nov;110(10):1389-98. doi: 10.1172/JCI16886.

DOI:10.1172/JCI16886
PMID:12438434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC151822/
Abstract
摘要

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Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis.挽救蛋白质构象:囊性纤维化药物治疗的前景
J Clin Invest. 2002 Dec;110(11):1591-7. doi: 10.1172/JCI16786.
2
Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy.α1-抗胰蛋白酶聚合与丝氨酸蛋白酶抑制剂病:病理生物学与治疗前景
J Clin Invest. 2002 Dec;110(11):1585-90. doi: 10.1172/JCI16782.
3
Liver injury in alpha1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury.α1-抗胰蛋白酶缺乏症中的肝损伤:一种聚集蛋白诱导线粒体损伤。
J Clin Invest. 2002 Dec;110(11):1579-83. doi: 10.1172/JCI16787.
4
Translational control in the endoplasmic reticulum stress response.内质网应激反应中的翻译调控。
J Clin Invest. 2002 Nov;110(10):1383-8. doi: 10.1172/JCI16784.
5
Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions.疾病中的蛋白质聚集:折叠中间体形成特定多聚体相互作用所起的作用。
J Clin Invest. 2002 Nov;110(9):1221-32. doi: 10.1172/JCI16781.
6
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Mol Cell. 2002 Jul;10(1):55-67. doi: 10.1016/s1097-2765(02)00583-x.
7
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Proc Natl Acad Sci U S A. 2002 Dec 10;99 Suppl 4(Suppl 4):16407-11. doi: 10.1073/pnas.152330499. Epub 2002 Jul 29.
8
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Dev Cell. 2002 Jul;3(1):99-111. doi: 10.1016/s1534-5807(02)00203-4.
10
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J Biol Chem. 2002 Sep 13;277(37):34287-94. doi: 10.1074/jbc.M204973200. Epub 2002 Jul 3.