de Souza Vanda Akico Ueda Fick, Fernandes Silvana, Araújo Evaldo Stanislau, Tateno Adriana Fumie, Oliveira Olímpia M N P F, Oliveira Renato Reis, Pannuti Cláudio Sérgio
Laboratório de Virologia (LIMHC-52), Instituto de Medicina Tropical de São Paulo, Brazil.
J Clin Microbiol. 2004 Apr;42(4):1782-4. doi: 10.1128/JCM.42.4.1782-1784.2004.
An enzyme-linked immunosorbent assay-based immunoglobulin G (IgG) antibody avidity test was evaluated by using sera from 57 patients with acute dengue infection. Overall, 55 of 57 patients were correctly classified (27 of 27 with primary dengue and 28 of 30 with secondary dengue). We conclude that the IgG avidity test can be useful for differentiating between acute, primary, and secondary dengue infections.
采用酶联免疫吸附试验对57例急性登革热感染患者的血清进行免疫球蛋白G(IgG)抗体亲和力检测评估。总体而言,57例患者中有55例分类正确(27例原发性登革热患者全部正确,30例继发性登革热患者中有28例正确)。我们得出结论,IgG亲和力检测有助于区分急性、原发性和继发性登革热感染。