Alimi Yves S, De Caridi Giovanni, Hartung Olivier, Barthèlemy Pierre, Aissi Karim, Otero Andres, Amer Maher, Giorgi Roch
Department of Vascular Surgery, Hópital Nord, Marseilles, France.
J Vasc Surg. 2004 Apr;39(4):777-83. doi: 10.1016/j.jvs.2003.10.053.
The purpose of this study was to evaluate the consequences on patient selection and on early and midterm results of the learning curve of a surgical team performing laparoscopy-assisted surgery in the treatment of severe aortoiliac occlusive disease (AIOD).
Between January 1998 and June 2003, 58 patients (53 men, 5 women; mean age, 59.5 years [range, 37-76 years]) were included in a prospective study and underwent a laparoscopy-assisted aortofemoral reconstruction with graft implantation through a 5-cm to 8-cm minilaparotomy. Fifty-one patients (88%) had claudication (category 2 or 3, Rutherford classification), and seven patients (12%) had tissue loss; at presentation they had TransAtlantic Inter-Society Consensus C (n=24, 41.4 %) or D (n=32, 55.2%) iliac lesions, and the last 2 patients (3.4%) had severe aortic lesions. Perioperative data for the first 29 patients, obtained during the first 34 months of the study (group 1), were compared with data for the last 29 patients, obtained during the last 32 months of the study (group 2). Follow-up consisted of clinical examination or duplex scanning, or both, at 1, 3, 6, and 12 months and yearly thereafter, and computed tomography before discharge and then every 2 years.
One intraoperative surgical conversion (1.7%) was necessary, and two other patients (3.4%) died in the immediate postoperative period. With experience, initial contraindications such as obesity or suprarenal artery aortic clamping were eliminated, making it possible to increase the percentage of patients included, from 53.7% during the first 34 months to 90.6% during the last 32 months (P=.003). The mean duration of the operative procedure decreased from 285 minutes in group 1 to 192 minutes in group 2 (P<.001), and the mean duration of aortic clamping decreased from 76.4 minutes in group 1 to 31.8 minutes in group 2 (P<.001). The number of early repeat interventions was reduced from three (10.3%) in group 1 to 2 (6.9%) in group 2 (P=NS), and the clinical recovery period decreased from 7 days to 4.5 days (P=.05). During a mean follow-up of 26.7 months (range, 1-66 months) there were 5 repeat surgeries (9%) to treat late graft occlusion, establishing midterm primary and secondary patency rates of 89.3% and 91%, respectively. No aortic false aneurysms were detected, and no major amputations were performed.
These preliminary results assess the feasability and the safety of this minimally invasive video-assisted technique. A short period of postoperative recovery and good midterm patency rate are the two main benefits of this new surgical option.
本研究旨在评估手术团队在进行腹腔镜辅助手术治疗严重主髂动脉闭塞性疾病(AIOD)时,学习曲线对患者选择以及早期和中期结果的影响。
在1998年1月至2003年6月期间,58例患者(53例男性,5例女性;平均年龄59.5岁[范围37 - 76岁])被纳入一项前瞻性研究,并通过5厘米至8厘米的小切口剖腹术接受腹腔镜辅助的主动脉股动脉重建及移植物植入。51例患者(88%)有间歇性跛行(2级或3级,卢瑟福分类),7例患者(12%)有组织缺失;就诊时,他们有跨大西洋跨学会共识C级(n = 24,41.4%)或D级(n = 32,55.2%)的髂动脉病变,最后2例患者(3.4%)有严重的主动脉病变。将研究前34个月期间纳入的前29例患者(第1组)的围手术期数据与研究最后32个月期间纳入的后29例患者(第2组)的数据进行比较。随访包括在1、3、6和12个月以及此后每年进行临床检查或双功超声扫描,或两者皆做,出院前及之后每2年进行计算机断层扫描。
有1例(1.7%)术中需转为开放手术,另外2例患者(3.4%)在术后即刻死亡。随着经验的积累,诸如肥胖或肾上腺动脉主动脉钳夹等最初的禁忌证被消除,从而使纳入患者的比例得以增加,从最初34个月期间的53.7%增至最后32个月期间的90.6%(P = 0.003)。手术平均时长从第1组的285分钟降至第2组的192分钟(P < 0.001),主动脉钳夹平均时长从第1组的76.4分钟降至第2组的31.8分钟(P < 0.001)。早期再次干预的次数从第1组的3次(10.3%)降至第2组的2次(6.9%)(P = 无统计学意义),临床恢复期从7天降至4.5天(P = 0.05)。在平均26.7个月(范围1 - 66个月)的随访期内,有5例(9%)患者接受再次手术以治疗晚期移植物闭塞,中期主要和次要通畅率分别为89.3%和91%。未检测到主动脉假性动脉瘤,也未进行大截肢手术。
这些初步结果评估了这种微创视频辅助技术的可行性和安全性。术后恢复时间短和中期通畅率良好是这种新手术方式的两个主要优点。