Mohan K Chandra, Shukla Dhananjay, Namperumalsamy P, Kim R
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Retina Vitreous Services, Madurai 625020.
J Indian Med Assoc. 2003 Aug;101(8):471-4, 476.
With the increase in life expectancy across the world, the magnitude of blindness due to age-related macular degeneration (AMD) is expected to rise. Exudative form is the major cause of visual loss from AMD. Several treatment options are available for this form of the disease. However, all treatment strategies aim at preservation of residual vision rather than regaining the lost vision. Two well-proven strategies are laser photocoagulation and photodynamic therapy. Other viable options are submacular surgery, transpupillary thermotherapy and pharmacological modalities like angiostatic-steroids. Oral anti-oxidants and zinc appear to be beneficial in preventing disease progression in early cases. Further research is on to explore more efficient treatments and to prove the safety and efficacy of large number of emerging newer treatment options.
随着全球人均寿命的增加,年龄相关性黄斑变性(AMD)导致的失明人数预计将会上升。渗出型是AMD导致视力丧失的主要原因。针对这种疾病形式有几种治疗选择。然而,所有治疗策略都旨在保留残余视力,而非恢复已丧失的视力。两种经过充分验证的策略是激光光凝和光动力疗法。其他可行的选择包括黄斑下手术、经瞳孔温热疗法以及诸如血管抑制类固醇等药物治疗方式。口服抗氧化剂和锌在预防早期病例的疾病进展方面似乎有益。目前正在进行进一步研究,以探索更有效的治疗方法,并证明大量新出现的治疗选择的安全性和有效性。