Piers Patricia A, Norrby N E Sverker, Mester Ulrich
Department of Applied Research, Pfizer Groningen BV, Van Swietenlaan 5, 9728 NX Groningen, The Netherlands.
Opt Lett. 2004 Apr 1;29(7):733-5. doi: 10.1364/ol.29.000733.
Theoretical calculations of the polychromatic modulation transfer function (MTF) and wave-front aberration were performed with physiological eye models. These eye models have an amount of spherical aberration that is representative of a normal population of pseudophakic eyes implanted with two different types of intraocular lens (IOL) made from high-refractive-index silicone. These theoretical calculations were compared with the measured contrast sensitivity function (CSF) under mesopic lighting conditions and with wave-front aberration (obtained with a Hartmann-Shack wave-front sensor) collected from 37 patients bilaterally implanted with the same types of lens. The relationships between the ocular wave-front aberration and the MTF predicted by the eye models and the CSF and the ocular wave-front aberration measured in eyes implanted with IOLs were investigated. The predicted improvements in MTF and wave-front aberration correlated well with the improvements measured in practice. Physiological eye models are therefore useful tools for IOL design.
使用生理眼模型对多色调制传递函数（MTF）和波前像差进行了理论计算。这些眼模型具有一定量的球差，该球差代表了植入两种不同类型由高折射率硅酮制成的人工晶状体（IOL）的假晶状体眼正常人群。将这些理论计算结果与在中间视觉照明条件下测得的对比敏感度函数（CSF）以及从37例双侧植入相同类型晶状体的患者中收集的波前像差（通过哈特曼-夏克波前传感器获得）进行了比较。研究了眼模型预测的眼波前像差与MTF之间的关系，以及在植入IOL的眼中测得的CSF与眼波前像差之间的关系。MTF和波前像差的预测改善与实际测量的改善高度相关。因此，生理眼模型是IOL设计的有用工具。
