Funada H
Protected Environment Unit, Kanazawa University School of Medicine.
Nihon Rinsho. 1992 May;50(5):1081-6.
Bacteremia due to methicillin-resistant Staphylococcus aureus (MRSA) is most likely to occur in compromised patients with prolonged hospitalization who are receiving antibiotics, particularly beta-lactam ones. The clinical picture of MRSA bacteremia is almost the same as that of bacteremia due to methicillin-sensitive S. aureus. There seems to be no significant difference in prognosis between the two types of staphylococcal bacteremia when patients in the same disease category are considered. Vancomycin is at present the only antibiotic for the treatment of MRSA bacteremia. It is therefore important to use the drug adequately so as to prevent its adverse effects and delay the appearance of resistant organisms.
耐甲氧西林金黄色葡萄球菌(MRSA)引起的菌血症最有可能发生在长期住院且正在接受抗生素治疗,尤其是β-内酰胺类抗生素治疗的免疫功能低下患者中。MRSA菌血症的临床表现与甲氧西林敏感金黄色葡萄球菌引起的菌血症几乎相同。当考虑同一疾病类别的患者时,这两种类型的葡萄球菌菌血症在预后方面似乎没有显著差异。目前,万古霉素是治疗MRSA菌血症的唯一抗生素。因此,合理使用该药物以预防其不良反应并延缓耐药菌的出现非常重要。