Kono K, Shiba K, Onuki K, Tohara S, Takeda S, Arakawa K, Nakashima H, Okuno T
Department of Internal Medicine, School of Medicine, Fukuoka University.
Nihon Rinsho. 1992 May;50(5):970-4.
Bacteriological and clinical studies were carried out on 280 strains of Staphylococcus aureus isolated in hospitals in Fukuoka city area from September 1990 to March 1991. Of all S. aureus strains studied 116 (41.4%) were methicillin-resistant. The proportion of MRSA in S. aureus isolates from outpatients was 10% (11/109), 69.2% (90/130) in those from inpatients. The average age of patients with isolated MRSA was 70.5 +/- 16.9 years and that of patients with isolated MSSA, 44.2 +/- 29.3. MRSA strains were recovered mainly from sputum and pus. The isolation rate did not vary significantly with hospitals of different size (number of beds). Of all MRSA strains 48 (41.3%) produced coagulase type VII. As for drug susceptibility, MRSA strains with coagulase type VII were more sensitive to clindamycin and more resistant to minocyclin compared to MRSA with other coagulase types.
对1990年9月至1991年3月在福冈市地区医院分离出的280株金黄色葡萄球菌进行了细菌学和临床研究。在所有研究的金黄色葡萄球菌菌株中，116株（41.4%）对甲氧西林耐药。门诊患者分离出的金黄色葡萄球菌中耐甲氧西林金黄色葡萄球菌（MRSA）的比例为10%（11/109），住院患者中为69.2%（90/130）。分离出MRSA的患者平均年龄为70.5±16.9岁，分离出甲氧西林敏感金黄色葡萄球菌（MSSA）的患者平均年龄为44.2±29.3岁。MRSA菌株主要从痰液和脓液中分离出来。不同规模（病床数量）医院的分离率无显著差异。在所有MRSA菌株中，48株（41.3%）产生VII型凝固酶。至于药敏性，与其他凝固酶类型的MRSA相比，VII型凝固酶的MRSA菌株对克林霉素更敏感，对米诺环素更耐药。
