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自闭症早期视觉皮层组织:一项功能磁共振成像研究。

Early visual cortex organization in autism: an fMRI study.

作者信息

Hadjikhani Nouchine, Chabris Christopher F, Joseph Robert M, Clark Jill, McGrath Lauren, Aharon Itzhak, Feczko Eric, Tager-Flusberg Helen, Harris Gordon J

机构信息

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Bldg. 36, First Street, Room 417, Charlestown, MA 02129, USA.

出版信息

Neuroreport. 2004 Feb 9;15(2):267-70. doi: 10.1097/00001756-200402090-00011.

DOI:10.1097/00001756-200402090-00011
PMID:15076750
Abstract

Autism is a neurodevelopmental disorder characterized by preserved visual abilities as well as a special profile for visual cognition. We examined the visual cortex of high-ability individuals with autism in order to assess whether the presence of abnormalities at the primary sensory level in autism could be the basis of their unusual pattern of visual cognitive abilities. We found that the early sensory visual areas are normally organized in individuals with autism, with a normal ratio between central versus peripheral visual field representation. We conclude that the differences observed in the visual capacities of individuals with autism are likely to arise from higher-level cognitive areas and functions, and are the result of top-down processes.

摘要

自闭症是一种神经发育障碍,其特征是具有保留的视觉能力以及特殊的视觉认知特征。我们研究了高能力自闭症个体的视觉皮层,以评估自闭症患者初级感觉水平上异常的存在是否可能是其异常视觉认知能力模式的基础。我们发现,自闭症个体的早期感觉视觉区域组织正常,中央与周边视野表征比例正常。我们得出结论,自闭症个体在视觉能力上观察到的差异可能源于更高层次的认知区域和功能,是自上而下过程的结果。

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