解脲脲原体（生物变种2）与非淋菌性尿道炎的关联。
Association of Ureaplasma urealyticum (biovar 2) with nongonococcal urethritis.
作者信息
Deguchi Takashi, Yoshida Takashi, Miyazawa Takamaro, Yasuda Mitsuru, Tamaki Masayoshi, Ishiko Hiroaki, Maeda Shin-Ichi
机构信息
Department of Urology, Gifu University School of Medicine, Gifu, Japan.
出版信息
Sex Transm Dis. 2004 Mar;31(3):192-5. doi: 10.1097/01.olq.0000114653.26951.71.
BACKGROUND
The tiny (T)-strain mycoplasmas, designated in 1974 as Ureaplasma urealyticum, have been divided into 2 species, Ureaplasma parvum (biovar 1) and U. urealyticum (biovar 2), but association of each of these species with nongonococcal urethritis (NGU) remains unclear.
GOAL
The goal of this study was to determine whether U. parvum (biovar 1) or U. urealyticum (biovar 2) is associated with NGU.
STUDY DESIGN
The prevalences of U. parvum (biovar 1) and U. urealyticum (biovar 2) in 572 patients with urethritis were compared with those in 141 men without urethritis.
RESULTS
The prevalence of U. urealyticum (biovar 2) in men with NGU (15.8%) or with nonchlamydial NGU (18.0%) was significantly higher than that in men without urethritis (7.8%). The prevalence of U. parvum (biovar 1) in men with NGU (8.5%) or with nonchlamydial NGU (11.1%) did not differ significantly from that in men without urethritis (13.5%).
CONCLUSION
Our results showed a significant association between U. urealyticum (biovar 2) and NGU. They also suggest that the presence of U. parvum (biovar 1) in the male urethra might be the result of colonization.
背景
微小（T）株支原体于1974年被命名为解脲脲原体，现已分为两个种，即微小脲原体（生物变种1）和解脲脲原体（生物变种2），但这两个种与非淋菌性尿道炎（NGU）的相关性仍不明确。
目的
本研究的目的是确定微小脲原体（生物变种1）或解脲脲原体（生物变种2）是否与NGU相关。
研究设计
比较了572例尿道炎患者中微小脲原体（生物变种1）和解脲脲原体（生物变种2）的患病率与141例无尿道炎男性的患病率。
结果
NGU男性（15.8%）或非衣原体性NGU男性（18.0%）中解脲脲原体（生物变种2）的患病率显著高于无尿道炎男性（7.8%）。NGU男性（8.5%）或非衣原体性NGU男性（11.1%）中微小脲原体（生物变种1）的患病率与无尿道炎男性（13.5%）相比无显著差异。
结论
我们的结果显示解脲脲原体（生物变种2）与NGU之间存在显著关联。它们还表明男性尿道中微小脲原体（生物变种1）的存在可能是定植的结果。
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