Yarzebski Jorge, Bujor Carmen F, Lessard Darleen, Gore Joel M, Goldberg Robert J
Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA.
Am Heart J. 2004 Apr;147(4):690-7. doi: 10.1016/j.ahj.2003.10.023.
Extremely limited population-based data are available describing recent and temporal trends in the characteristics, treatment, and outcomes of Hispanic and non-Hispanic white patients hospitalized with acute myocardial infarction (AMI).
This was a community-based, observational study of 9649 greater Worcester residents hospitalized in all hospitals serving the Worcester, Massachusetts, metropolitan area in 12 one-year periods between 1975 and 1999. In the total study sample, 171 (2%) patients were Hispanic. Hispanic patients were matched with 395 non-Hispanic white patients on the basis of age, sex, and year of hospitalization.
Hispanics were more likely to present to greater Worcester hospitals with a history of diabetes as compared with non-Hispanic whites. Hispanics were less likely to have an initial, Q-wave AMI during the index hospitalization. After controlling for a limited number of known potentially confounding factors, Hispanics were at lower risk for development of heart failure (OR, 0.63; 95% CI, 0.41, 0.96). Both Hispanics (13% vs 11%) and non-Hispanic whites (28% vs 9%), however, had declines in hospital case-fatality rates between 1975 and 1999. An overall similar treatment pattern and increasing trends in the use of effective cardiac medications over time were observed in both patient groups. However, Hispanics were significantly less likely to be treated with coronary angioplasty during the acute hospitalization. Trends of a worse long-term survival for discharged Hispanic patients were observed over a 10-year follow-up period.
The results of this community-wide study suggest encouraging hospital outcomes in Hispanic and non-Hispanic white patients hospitalized with AMI. Enhanced secondary prevention efforts remain needed to improve the hospital and long-term outcomes of patients with AMI, irrespective of race or ethnicity.
关于因急性心肌梗死(AMI)住院的西班牙裔和非西班牙裔白人患者的特征、治疗及预后的近期和时间趋势,基于人群的数据极其有限。
这是一项基于社区的观察性研究,研究对象为1975年至1999年期间在马萨诸塞州伍斯特市大都市地区所有医院住院的9649名伍斯特市居民。在整个研究样本中,171名(2%)患者为西班牙裔。根据年龄、性别和住院年份,将西班牙裔患者与395名非西班牙裔白人患者进行匹配。
与非西班牙裔白人相比,西班牙裔患者更有可能因糖尿病史而前往伍斯特市的医院就诊。西班牙裔患者在首次住院期间发生初始Q波心肌梗死的可能性较小。在控制了数量有限的已知潜在混杂因素后,西班牙裔患者发生心力衰竭的风险较低(比值比,0.63;95%可信区间,0.41,0.96)。然而,在1975年至1999年期间,西班牙裔患者(13%对11%)和非西班牙裔白人患者(28%对9%)的医院病死率均有所下降。在两组患者中均观察到总体相似的治疗模式以及随着时间推移有效心脏药物使用的增加趋势。然而,西班牙裔患者在急性住院期间接受冠状动脉成形术治疗的可能性显著较低。在10年的随访期内,观察到出院的西班牙裔患者长期生存情况较差的趋势。
这项全社区研究的结果表明,因AMI住院的西班牙裔和非西班牙裔白人患者的医院预后令人鼓舞。仍需要加强二级预防措施,以改善AMI患者的医院和长期预后,无论其种族或族裔如何。