Grossmann Georg, Hoffmeister Albrecht, Imhof Armin, Giesler Martin, Hombach Vinzenz, Spiess Jochen
Department of Internal Medicine, Division of Cardiology, University of Ulm, Ulm, Germany.
Am Heart J. 2004 Apr;147(4):721-8. doi: 10.1016/j.ahj.2003.11.006.
The follow-up of patients with mitral and tricuspid regurgitation is important for their clinical treatment. We aimed to evaluate the reproducibility of the flow convergence method in mitral and tricuspid regurgitation.
The proximal flow convergence region was imaged with color Doppler ultrasound scanning echocardiography in 83 patients with mitral regurgitation, tricuspid regurgitation, or both. Proximal isovelocity surface area radii for aliasing velocities of 27 to 29 cm/s and 41 to 43 cm/s were repeatedly measured by the same experienced investigator on different days and by experienced and less experienced investigators at 1 day.
In mitral regurgitation, the intraobserver variability rate was 0.2% +/- 13.5% (2.8% +/- 13.3%) and the interobserver variability was 0.1% +/- 13.8% (1.7% +/- 18.0%) for an aliasing velocity of 27 to 29 cm/s (41-43 cm/s). For the aliasing velocity of 27 to 29 cm/s (41-43 cm/s), the 95% ranges for change of the proximal isovelocity surface area radii were +/- 2.7 mm (+/- 1.8 mm) for measurements repeated by the same investigator and +/- 2.7 mm ( +/- 2.4 mm) for different investigators. Interobserver variability was independent of the investigators' experience. Similar data were achieved in tricuspid regurgitation.
The proximal flow convergence method is acceptably reproducible in mitral and tricuspid regurgitation independent of the investigators experience. For the aliasing velocity of 27 to 29 cm/s (41-43 cm/s), the proximal isovelocity surface area radius has to change for >2.7 (2.4) mm before an altered severity of mitral or tricuspid regurgitation in a single patient can be assumed.
二尖瓣和三尖瓣反流患者的随访对其临床治疗很重要。我们旨在评估血流会聚法在二尖瓣和三尖瓣反流中的可重复性。
对83例患有二尖瓣反流、三尖瓣反流或两者兼有的患者,用彩色多普勒超声心动图扫描对近端血流会聚区进行成像。由同一位经验丰富的研究者在不同日期,以及由经验丰富和经验较少的研究者在同一天,对27至29 cm/s和41至43 cm/s的混叠速度下的近端等速表面积半径进行重复测量。
在二尖瓣反流中,对于27至29 cm/s(41 - 43 cm/s)的混叠速度,观察者内变异性率为0.2%±13.5%(2.8%±13.3%),观察者间变异性为0.1%±13.8%(1.7%±18.0%)。对于27至29 cm/s(41 - 43 cm/s)的混叠速度,同一研究者重复测量时近端等速表面积半径变化的95%范围为±2.7 mm(±1.8 mm),不同研究者测量时为±2.7 mm(±2.4 mm)。观察者间变异性与研究者的经验无关。三尖瓣反流中获得了类似的数据。
近端血流会聚法在二尖瓣和三尖瓣反流中具有可接受的可重复性,与研究者的经验无关。对于27至29 cm/s(41 - 43 cm/s)的混叠速度,在假设单例患者二尖瓣或三尖瓣反流严重程度改变之前,近端等速表面积半径必须改变>2.7(2.4)mm。