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[右房室瓣功能不全病例中近端加速法的应用]

[The use of the proximal acceleration method in cases of incompetence of the right atrioventricular valve].

作者信息

Rivera J M, Vandervoort P M, Morris E, Weyman A E, Thomas J D

机构信息

Centro de Investigación Cardiocirculatoria, Hospital La Fe, Valencia.

出版信息

Rev Esp Cardiol. 1994 Sep;47(9):597-603.

PMID:7973026
Abstract

BACKGROUND

Quantitation of valvular regurgitation remains an important goal in cardiology. It has been described previously that using color Doppler flow mapping, measurements of apparent jet size do not correlate always closely with quantitative regurgitant indexes. Recently the proximal flow convergence method has been proposed to quantify valvular regurgitation by analysis of the converging flow field proximal to a regurgitant lesion. Assuming hemispherical convergence, peak flow rate Qp can be calculated as Qp = 2 pi r2Va, where Va is the aliasing velocity at a distance r from the orifice. For maximal accuracy, previously validated correction factors must be used to account for the flattening effect of the isovelocity contours close to the orifice and for the actual sector angle subtended by the valve leaflets (alpha) to yield a flow rate formula Qp = 2 pi r2Va (Vp/Vp-Va) (alpha/180), where Vp is the orifice velocity obtained by continuous wave Doppler.

METHODS

In 45 patients (35 in sinus rhythm, 10 with atrial fibrillation) with tricuspid regurgitation, regurgitant stroke volume, regurgitant flow rate were calculated using the proximal flow convergence method and compared with values obtained by the Doppler two-dimensional echocardiographic method.

RESULTS

Regurgitant stroke volumes (SV) calculated by the proximal flow convergence method correlated very closely with values obtained by the Doppler two-dimensional method with r = 0.95 (y = 0.94x + 0.99) and delta SV = -0.3 +/- 5.2 cm3. Regurgitant flow rates (Q) calculated by both methods showed a similar correlation: r = 0.96 (y = 0.97x + 45) and delta Q = 1.6 +/- 4.29 cm3/min. All correlations were slightly better for the group of patients in sinus rhythm.

CONCLUSION

This study demonstrates that the proximal flow convergence method is an accurate and reproducible technique for quantifying tricuspid regurgitation. While improvements of this method are to be expected, flow calculations based on the proximal flow field show excellent results and appear appropriate for clinical use.

摘要

背景

瓣膜反流的定量分析仍是心脏病学中的一个重要目标。此前已有描述称,使用彩色多普勒血流显像时,表观射流大小的测量值并不总是与反流定量指标密切相关。最近有人提出采用近端血流会聚法,通过分析反流病变近端的会聚流场来定量瓣膜反流。假设为半球形会聚,峰值流速Qp可计算为Qp = 2πr2Va,其中Va是距瓣口距离为r处的血流速度峰值。为获得最大准确性,必须使用先前验证过的校正因子,以考虑靠近瓣口的等速线的扁平化效应以及瓣膜小叶所对的实际扇形角度(α),从而得出流速公式Qp = 2πr2Va(Vp/Vp - Va)(α/180),其中Vp是通过连续波多普勒获得的瓣口速度。

方法

对45例三尖瓣反流患者(35例为窦性心律,10例为心房颤动),采用近端血流会聚法计算反流搏出量和反流流速,并与二维多普勒超声心动图法测得的值进行比较。

结果

近端血流会聚法计算出的反流搏出量(SV)与二维多普勒法测得的值密切相关,r = 0.95(y = 0.94x + 0.99),ΔSV = -0.3 ± 5.2 cm3。两种方法计算出的反流流速(Q)显示出相似的相关性:r = 0.96(y = 0.97x + 45),ΔQ = 1.6 ± 4.29 cm3/min。窦性心律患者组的所有相关性略好。

结论

本研究表明,近端血流会聚法是一种准确且可重复的三尖瓣反流定量技术。虽然预计该方法会有所改进,但基于近端流场的流量计算显示出优异的结果,似乎适合临床应用。

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