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减轻不同严重程度膝关节骨关节炎患者内侧间室负荷的潜在策略:降低步行速度。

Potential strategies to reduce medial compartment loading in patients with knee osteoarthritis of varying severity: reduced walking speed.

作者信息

Mündermann Anne, Dyrby Chris O, Hurwitz Debra E, Sharma Leena, Andriacchi Thomas P

机构信息

Stanford University, Stanford, California 94305-3030, USA.

出版信息

Arthritis Rheum. 2004 Apr;50(4):1172-8. doi: 10.1002/art.20132.

Abstract

OBJECTIVE

To determine whether reducing walking speed is a strategy used by patients with knee osteoarthritis (OA) of varying disease severity to reduce the maximum knee adduction moment.

METHODS

Self-selected walking speeds and maximum knee adduction moments of 44 patients with medial tibiofemoral OA of varying disease severity, as assessed by using the Kellgren/Lawrence grade, were compared with those of 44 asymptomatic control subjects matched for sex, age, height, and weight.

RESULTS

Differences in self-selected normal walking speed explained only 8.9% of the variation in maximum knee adduction moment for the group of patients with knee OA. The severity of the disease influenced the adduction moment-walking speed relationship; the individual slopes of this relationship were significantly greater in patients with less severe OA than in asymptomatic matched control subjects. Self-selected walking speed did not differ between patients with knee OA, regardless of the severity, and asymptomatic control subjects. However, knees with more-severe OA had significantly greater adduction moments (mean +/- SD 3.80 +/- 0.89% body weight x height) and were in more varus alignment (6.0 +/- 4.5 degrees ) than knees with less-severe OA (2.94 +/- 0.70% body weight x height; and 0.0 +/- 2.9 degrees, respectively).

CONCLUSION

Patients with less-severe OA adapt a walking style that differs from that of patients with more-severe OA and controls. This walking style is associated with the potential to reduce the adduction moment when walking at slower speeds and could be linked to decreased disease severity.

摘要

目的

确定降低步行速度是否是不同疾病严重程度的膝骨关节炎(OA)患者用来降低最大膝关节内收力矩的一种策略。

方法

将44例根据Kellgren/Lawrence分级评估的不同疾病严重程度的胫股内侧OA患者的自我选择步行速度和最大膝关节内收力矩,与44例年龄、性别、身高和体重匹配的无症状对照者进行比较。

结果

在膝OA患者组中,自我选择的正常步行速度差异仅解释了最大膝关节内收力矩变化的8.9%。疾病严重程度影响内收力矩与步行速度的关系;病情较轻的OA患者这种关系的个体斜率显著大于无症状匹配对照者。无论疾病严重程度如何,膝OA患者与无症状对照者的自我选择步行速度无差异。然而,与病情较轻的OA患者相比,病情较重的OA患者膝关节内收力矩显著更大(平均±标准差为3.80±0.89%体重×身高),内翻角度更大(6.0±4.5度)(病情较轻的OA患者分别为2.94±0.70%体重×身高和0.0±2.9度)。

结论

病情较轻的OA患者采用的步行方式与病情较重的OA患者及对照者不同。这种步行方式与较慢步行速度时降低内收力矩的可能性有关,可能与疾病严重程度降低有关。

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