Safronova L A, Poltavs'kyĭ O M, Tsaruk'ianova I H, Savychuk O V, Sten'kina S Ie, Smyrnova O V
Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154 Zabolotny St., 03143, Kyiv, Ukraine.
Mikrobiol Z. 2003 Nov-Dec;65(6):49-58.
Peculiarities of quantitative and qualitative composition of microbiocenosis of the oral cavity in healthy children and children with chronic aphthous recurrent stomatitis have been studied. Strains of microorganisms (n = 259) have been isolated and identified. The results obtained showed that the studied biotope is characterised by a wide spectrum of isolated microflora. The growth of microorganism association is observed in all the studied samples. The analysis of genus and species composition of microbiocenosis of the mucous membrane indicated that streptococci, neiserii, corynebacteria, enterococci, lactobacilli, epidermal staphylococci and candidas were distinguished as to isolation frequency among the isolated strains. These bacteria were isolated from oral cavity of healthy and sick children, but their quantity in 1 mm2 of sick children mucosa prevailed, except for Streptococcus salivarius, S. mitis and Lactobacillus sp.: their quantity was far less. Golden staphylococci, escherichia, klebsiella, clostridia, hemophilic rods and campylobacteria were isolated from sick children only.
对健康儿童和患有慢性复发性阿弗他口炎的儿童口腔微生物群落的定量和定性组成特点进行了研究。已分离并鉴定出微生物菌株（n = 259）。所得结果表明，所研究的生物群落具有广泛的分离微生物区系特征。在所有研究样本中均观察到微生物群落的生长。对黏膜微生物群落的属和种组成分析表明，在分离出的菌株中，链球菌、奈瑟菌、棒状杆菌、肠球菌、乳杆菌、表皮葡萄球菌和念珠菌在分离频率上较为突出。这些细菌在健康和患病儿童的口腔中均有分离，但在患病儿童每平方毫米黏膜中的数量占优势，唾液链球菌、缓症链球菌和乳杆菌属除外：它们的数量要少得多。仅在患病儿童中分离出金黄色葡萄球菌、大肠杆菌、克雷伯菌、梭菌、嗜血性杆菌和弯曲杆菌。
