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伊曲康唑治疗肺部米根霉感染完全缓解:唑类药物治疗接合菌病有效性的更多证据

Complete resolution of pulmonary Rhizopus oryzae infection with itraconazole treatment: more evidence of the utility of azoles for zygomycosis.

作者信息

Eisen D P, Robson J

机构信息

Infectious Diseases Unit, Royal Brisbane Hospital, Herston, Queensland, Australia.

出版信息

Mycoses. 2004 Apr;47(3-4):159-62. doi: 10.1111/j.1439-0507.2004.00959.x.

DOI:10.1111/j.1439-0507.2004.00959.x
PMID:15078434
Abstract

Zygomycosis often requires aggressive surgical and antifungal therapy. We report a non-neutropenic patient with myelodysplastic syndrome and iron overload receiving cytotoxic therapy who presented with pulmonary Rhizopus oryzae infection. This patient was cured through the use of itraconazole alone and the literature on the utility of azole antifungals for zygomycosis is reviewed.

摘要

接合菌病通常需要积极的手术和抗真菌治疗。我们报告了一名患有骨髓增生异常综合征和铁过载且正在接受细胞毒性治疗的非中性粒细胞减少患者,该患者出现了米根霉肺部感染。该患者仅通过使用伊曲康唑就得以治愈,并且对唑类抗真菌药物治疗接合菌病的效用相关文献进行了综述。

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