Arushanian E B
Pharmacology Department, Stavropol State Medical Academy, ul. Mira 310, Stavropol, 355017 Russia.
Eksp Klin Farmakol. 2004 Jan-Feb;67(1):54-60.
The review summarizes data on the nature of chronotropic properties of psychostimulants. Mechanisms underlying the ability of these drugs to shift the normal ratio in the rest--activity cycle toward wakeful phase and factors determining the dependence of the drug effect on the circadian variations of pharmacokinetics are considered.
这篇综述总结了关于精神兴奋药变时性特性本质的数据。考虑了这些药物将静息-活动周期的正常比例向清醒阶段转变的能力背后的机制,以及决定药物效应依赖于药代动力学昼夜变化的因素。