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与血管紧张素转换酶抑制剂相关的危及生命的舌血管性水肿。

Life threatening tongue angioedema associated with an angiotensin-converting enzyme inhibitor.

作者信息

Yanturali Sedat, Ergun Nurdan, Eminoglu Ozlem, Kalkan Sule, Tuncok Yesim

机构信息

Dokuz Eylul University School of Medicine, Department of Pharmacology, Izmir, Turkey.

出版信息

Vet Hum Toxicol. 2004 Apr;46(2):85-6.

Abstract

We present a case with angioedema of the tongue, following 1 dose of an angiotensin-converting enzyme (ACE) inhibitor ingestion. A gradual progression of angioedema required tracheotomy despite aggressive medical treatment and illustrates the severity of this adverse reaction. Although ACE inhibitors are considered safe, emergency physicians should be alert for minor angioedema at presentation that may progress to life threatening airway compromise.

摘要

我们报告一例在服用一剂血管紧张素转换酶(ACE)抑制剂后出现舌血管性水肿的病例。尽管进行了积极的药物治疗,但血管性水肿仍逐渐进展,最终需要进行气管切开术,这说明了这种不良反应的严重性。虽然ACE抑制剂被认为是安全的,但急诊医生在接诊时应警惕轻微的血管性水肿,因为其可能进展为危及生命的气道梗阻。

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