Bauwens L J, Copper M P, Schmidt J T
Westfries Gasthuis, afd. Keel-, Neus- en Oorheelkunde, Hoorn.
Ned Tijdschr Geneeskd. 1995 Apr 1;139(13):674-7.
During the past years, angioedema occurring in association with angiotensin converting enzyme (ACE) inhibitors is seen more and more often. This is due to the increasing use of these drugs for hypertension and congestive heart failure. If the diagnosis is missed and prescription of the ACE inhibitor is prolonged, recurrent and more severe episodes of angioedema may occur. In case of involvement of the upper airway and respiratory distress, the condition may be life-threatening. We demonstrate three such patients, men of 84, 73 and 63 years old. First of all, the airway should be secured. Administration of epinephrine may be indicated. Further use of ACE inhibitors is contraindicated.
在过去几年中，与血管紧张素转换酶（ACE）抑制剂相关的血管性水肿越来越常见。这是由于这些药物在高血压和充血性心力衰竭治疗中的使用日益增加。如果漏诊且ACE抑制剂的处方持续时间延长，可能会发生血管性水肿的复发且更严重的发作。如果上呼吸道受累并出现呼吸窘迫，病情可能危及生命。我们展示了三位这样的患者，年龄分别为84岁、73岁和63岁的男性。首先，应确保气道安全。可能需要使用肾上腺素。禁忌进一步使用ACE抑制剂。
