Tuteja A K, Rao S S C
VA Salt Lake Health Care System and the University of Utah, Salt Lake City, UT, USA.
Aliment Pharmacol Ther. 2004 Apr 15;19(8):829-40. doi: 10.1111/j.1365-2036.2004.01931.x.
The inability to control bowel discharge is not only common but extremely distressing. It has a negative impact on a patient's lifestyle, leads to a loss of self-esteem, social isolation and a diminished quality of life. Faecal incontinence is often due to multiple pathogenic mechanisms and rarely due to a single factor. Normal continence to stool is maintained by the structural and functional integrity of the anorectal unit. Consequently, disruption of the normal anatomy or physiology of the anorectal unit leads to faecal incontinence. Currently, several diagnostic tests are available that can provide an insight regarding the pathophysiology of faecal incontinence and thereby guide management. The treatment of faecal incontinence includes medical, surgical or behavioural approaches. Today, by using logical approach to management, it is possible to improve symptoms and bowel function in many of these patients.
无法控制排便不仅常见，而且极其令人苦恼。它会对患者的生活方式产生负面影响，导致自尊丧失、社交孤立以及生活质量下降。大便失禁通常是由多种致病机制引起的，很少由单一因素导致。正常的大便节制是通过肛门直肠单元的结构和功能完整性来维持的。因此，肛门直肠单元正常解剖结构或生理功能的破坏会导致大便失禁。目前，有几种诊断测试可供使用，这些测试可以深入了解大便失禁的病理生理学，从而指导治疗。大便失禁的治疗包括药物、手术或行为方法。如今，通过采用合理的治疗方法，可以改善许多此类患者的症状和肠道功能。
