Mancini M L, Bartolini M, Tambasco N, Gallai V
Department of Neuroscience, University of Perugia, Perugia, Italy.
J Clin Neurosci. 2004 May;11(4):364-7. doi: 10.1016/j.jocn.2002.05.001.
The quantitative assessment of tremor represents the main difficulty in clinical evaluation. We developed a software package - T-Lab - for the biomechanical analysis of hyperkinetic movement disorders. This software can receive and elaborate data from an electronic device interfaced with a personal computer. The aim of our study was to verify the validity of the PC-aided method proposed in the routine assessment of tremor. We did this by a correlation (regression) analysis between the scores obtained by Webster's Amplitude Clinical Scale and the amplitude data by T-Lab and between EMG data and frequency measures of T-Lab. Forty-seven patients presenting with upper limb tremor were enrolled. Four series of data were obtained: two series for frequency and two for amplitude. A significant correlation between all sets of data compared was found. T-Lab represents a valid, objective and useful device of quantifying tremors in clinical practice.
震颤的定量评估是临床评估中的主要难点。我们开发了一个软件包——T-Lab,用于对运动亢进性运动障碍进行生物力学分析。该软件可以接收并处理来自与个人计算机相连的电子设备的数据。我们研究的目的是验证在震颤的常规评估中所提出的计算机辅助方法的有效性。我们通过对韦伯斯特振幅临床量表所获分数与T-Lab的振幅数据之间以及肌电图数据与T-Lab的频率测量值之间进行相关性(回归)分析来实现这一点。招募了47例上肢震颤患者。获得了四组数据:两组频率数据和两组振幅数据。在所比较的所有数据集之间均发现了显著相关性。T-Lab是临床实践中一种有效、客观且有用的震颤量化设备。