Harty R F
Arch Intern Med. 1978 Sep;138(9):1424-6.
Sclerosing peritonitis developed in a 43-year-old man with angina pectoris who had been receiving the beta-adrenergic receptor antagonist, propranolol. The patient had abdominal and back pain, weight loss, a midabdominal fullness, ascites, and evidence of partial small bowel obstruction. At surgery, the small bowel was distended and encased by dense fibrous tissue. Infectious and neoplastic causes of fibrosing peritoneal inflammation were excluded. The patient described in this report illustrates several features commonly experienced by individuals who developed sclerosing peritonitis associated with beta-adrenergic receptor blockade therapy. To my knowledge, the development of ascites and considerable ascitic fluid leukocytosis have not been described previously with this disorder.
一名患有心绞痛的43岁男性在接受β-肾上腺素能受体拮抗剂普萘洛尔治疗时发生了硬化性腹膜炎。该患者有腹痛、背痛、体重减轻、中腹部饱满、腹水以及部分小肠梗阻的迹象。手术时,小肠扩张并被致密的纤维组织包裹。排除了纤维化性腹膜炎症的感染性和肿瘤性病因。本报告中描述的患者体现了与β-肾上腺素能受体阻滞剂治疗相关的硬化性腹膜炎患者通常会出现的几个特征。据我所知,此前尚未有关于这种疾病出现腹水和大量腹水白细胞增多的报道。