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DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase.
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V(D)J recombination and RAG-mediated transposition in yeast.
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Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.
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4
The C-terminal portion of RAG2 protects against transposition in vitro.
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Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2.
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Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice.
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Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination.
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Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase.
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Does artemis end the hunt for the hairpin-opening activity in V(D)J recombination?
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