Scourfield Jane, Martin Neilson, Eley Thalia C, McGuffin Peter
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK.
Behav Genet. 2004 Jul;34(4):377-83. doi: 10.1023/B:BEGE.0000023643.49413.df.
Studies of children and adolescents with conduct problems suggest both genetic and environmental influences on population variance. Any genetic influence is likely to be complex and to act via mediating attributes of personality or cognitive style. One potential mediating attribute is social cognitive ability, as conduct problems have been shown to be associated with deficient social cognitive skills. The current investigation has examined the correlation between conduct problems and social cognition and has investigated the genetic and environmental influences on these measures and their covariation using a twin design. A population-based sample of twins aged 5-17 was used to examine the genetic relationship between conduct problems and social cognition using parent-report questionnaires. Conduct problems and social cognition were found to be highly correlated and to share common genetic influences that accounted for about half the covariation in scores. Each phenotype was subject to its own environmental influences that were not shared.
对有行为问题的儿童和青少年的研究表明，基因和环境对群体差异均有影响。任何基因影响都可能很复杂，并通过个性或认知风格的中介属性起作用。一个潜在的中介属性是社会认知能力，因为行为问题已被证明与社会认知技能缺陷有关。当前的调查研究了行为问题与社会认知之间的相关性，并使用双胞胎设计研究了基因和环境对这些指标及其协变的影响。以一个基于人群的5至17岁双胞胎样本为基础，使用父母报告问卷来研究行为问题与社会认知之间的基因关系。研究发现，行为问题与社会认知高度相关，且共享约占分数协变一半的共同基因影响。每个表型都受到其自身独有的环境影响。
