Rotella David P
Lexicon Pharmaceuticals, 350 Carter Road, Princeton, NJ 08540, USA.
Curr Opin Investig Drugs. 2004 Mar;5(3):348-51.
SB-480848 is a reversible lipoprotein-associated phospholipase A2 inhibitor under development by GlaxoSmithKline for the potential treatment of atherosclerosis. Phase II trials with SB-480848 are currently underway.
SB - 480848是葛兰素史克公司正在研发的一种可逆性脂蛋白相关磷脂酶A2抑制剂,用于潜在治疗动脉粥样硬化。目前正在进行SB - 480848的二期试验。