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在一个新发展的国家中,高血压作为充血性心力衰竭患者10年风险预测指标的作用。

The effect of hypertension as a predictor of risk for congestive heart failure patients over a 10-year period in a newly developed country.

作者信息

Bener A, al Suwaidi J, el-Menyar A, Gehani A

机构信息

Department of Medical Statistics & Epidemiology, Hamad General Hospital, Hamad Medical Corporation, Doha, State of Qatar.

出版信息

Blood Press. 2004;13(1):41-6. doi: 10.1080/08037050310028462.

DOI:10.1080/08037050310028462
PMID:15083640
Abstract

AIMS

Cardiovascular disease is the leading cause of mortality and morbidity in the western world and has reached epidemic proportions. The incidence of congestive heart failure (CHD) and hypertension is also rising rapidly in many of the affluent Arab nations and cardiovascular diseases continue to be a leading cause of morbidity and mortality among adult Qataris and Asians residing in Qatar.

OBJECTIVE

The objective of this study is to assess the effect of hypertension among patients admitted to hospital in Qatar with CHD and to identify risk factors that contribute to the development of CHD in hypertensive subjects.

DESIGN

This is a retrospective cohort study.

SETTING

Hamad General Hospital, Hamad Medical Corporation.

SUBJECTS

All patients who were hospitalized with CHD with or without hypertension in the Hamad General Hospital, State of Qatar, from 1991 to 2001.

METHODS

The diagnostic classification of definite CHD was made in accordance with criteria based on the International Classification of Disease, ninth revision (ICD-9].

RESULT

A total of 20,856 patients were treated during the 10-year period; 8446 were Qataris. Among them, 60% were males and 40% females. Among the total patients (3713) hospitalized with CHD, 1744 (46.9%) had hypertension. Furthermore, the incidence of hypertension was slightly higher in males than in females (56.4 vs 43.6%). A statistically significant difference was found between hypertensive and non-hypertensive cases with diabetes mellitus and angina. Hypertensive subjects were more likely to have diabetes (p < 0.001) and angina (p < 0.030). The mortality rate of CHD patients with hypertension was higher among Qataris than among non-Qataris (p < 0.038).

CONCLUSION

Hypertension was the most common risk factor for CHD; it contributed a large proportion of heart failure cases in this population-based sample. Preventive strategies directed toward earlier detection of elevated blood pressure and its control are likely to offer the greatest promise for reducing the incidence of CHD and its associated mortality.

摘要

目的

心血管疾病是西方世界死亡率和发病率的主要原因,且已达到流行程度。在许多富裕的阿拉伯国家,充血性心力衰竭(CHD)和高血压的发病率也在迅速上升,心血管疾病仍然是卡塔尔成年人和居住在卡塔尔的亚洲人发病和死亡的主要原因。

目标

本研究的目的是评估卡塔尔因冠心病住院患者中高血压的影响,并确定导致高血压患者患冠心病的危险因素。

设计

这是一项回顾性队列研究。

地点

哈马德医疗公司哈马德总医院。

研究对象

1991年至2001年期间在卡塔尔国哈马德总医院因冠心病住院的所有患者,无论有无高血压。

方法

根据基于国际疾病分类第九版(ICD - 9)的标准进行明确冠心病的诊断分类。

结果

在这10年期间共治疗了20856名患者;其中8446名是卡塔尔人。其中,60%为男性,40%为女性。在因冠心病住院的全部患者(3713名)中,1744名(46.9%)患有高血压。此外,男性高血压发病率略高于女性(56.4%对43.6%)。在患有糖尿病和心绞痛的高血压和非高血压病例之间发现了统计学上的显著差异。高血压患者更易患糖尿病(p < 0.001)和心绞痛(p < 0.030)。卡塔尔籍冠心病高血压患者的死亡率高于非卡塔尔籍患者(p < 0.038)。

结论

高血压是冠心病最常见的危险因素;在这个基于人群的样本中,它导致了很大比例的心力衰竭病例。针对早期发现血压升高并加以控制的预防策略,可能为降低冠心病发病率及其相关死亡率带来最大希望。

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