Wennberg A, Hagman M, Johansson L
Department of Neuromedicine, National Institute of Occupational Health, Solna, Sweden.
Neurotoxicology. 1992 Spring;13(1):271-4.
To study the effects from low level exposure to manganese, 30 men at steel smelting works and 60 nonexposed reference subjects, were neurophysiologically examined using: (i) Electroencephalogram (EEG), Event related auditory evoked potential (AEP/P300), Brain stem auditory evoked potential (BAEP) and diadochokinesometry. No group differences concerning EEG or BAEP were found. Diadochokinesis was slower and there was a tendency towards prolonged P300 latency in the exposed group as compared to the referents. These effects may be interpreted as early (subclinical) signs of disturbances of the same type as parkinsonism.
为研究低水平接触锰的影响，对30名钢铁冶炼厂工人和60名未接触锰的对照对象进行了神经生理学检查，采用了以下方法：（i）脑电图（EEG）、事件相关听觉诱发电位（AEP/P300）、脑干听觉诱发电位（BAEP）和轮替运动速率测定。未发现两组在脑电图或脑干听觉诱发电位方面存在差异。与对照对象相比，接触组的轮替运动较慢，且P300潜伏期有延长的趋势。这些影响可被解释为与帕金森病同类型的早期（亚临床）功能障碍迹象。
