Elia-Pasquet Sandrine, Provost Dorothée, Jaffré Anne, Loiseau Hugues, Vital Anne, Kantor Guy, Maire Jean-Philippe, Dautheribes Michel, Darrouzet Vincent, Dartigues Jean-François, Brochard Patrick, Baldi Isabelle
Laboratoire Santé Travail Environnement, Institut de Santé Publique d'Epidémiologie et du Développement, Université Victor Segalen Bordeaux 2, Bordeaux, France.
Neuroepidemiology. 2004 May-Jun;23(3):110-7. doi: 10.1159/000075953.
The incidence of CNS tumors is subject to geographical and temporal variations which are poorly understood. The incidence of these tumors was studied in Gironde, a department of southwestern France with 1,058,911 inhabitants older than 16 years. We recorded any malignant or benign central nervous system (CNS) tumor diagnosed between May 1999 and April 2001 in adults living in Gironde. Three hundred and twenty-nine CNS tumors were diagnosed during the study period. The incidence of CNS tumors in adults was therefore 15.5 per 100,000. Overall, the incidence according to sex was 14.7 for males and 16.2 per 100,000 for females. The incidence rate increased according to age up to 80 years (3.7 per 100,000 for 20-29 years of age to 33.4 per 100,000 for 70-79 years of age) and reduced thereafter for gliomas. Our estimation of the incidence of CNS tumors ranks high among the earlier reports. Further analytic studies are ongoing.
中枢神经系统肿瘤的发病率存在地理和时间差异，目前对此了解甚少。我们在法国西南部的吉伦特省对这些肿瘤的发病率进行了研究，该省有1,058,911名16岁以上的居民。我们记录了1999年5月至2001年4月期间在吉伦特省居住的成年人中诊断出的任何恶性或良性中枢神经系统（CNS）肿瘤。在研究期间共诊断出329例中枢神经系统肿瘤。因此，成年人中枢神经系统肿瘤的发病率为每10万人15.5例。总体而言，按性别划分的发病率为男性每10万人14.7例，女性每10万人16.2例。发病率随年龄增长至80岁而上升（20 - 29岁年龄组为每10万人3.7例，70 - 79岁年龄组为每10万人33.4例），此后胶质瘤的发病率有所下降。我们对中枢神经系统肿瘤发病率的估计在早期报告中排名靠前。进一步的分析研究正在进行中。
