Sohn Seil, Kim Jinhee, Chung Chun Kee, Lee Na-Rye, Park Eunjung, Chang Ung-Kyu, Sohn Moon Jun, Kim Sung Hwan
Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea (S.S., C.K.C.); Neuroscience Research Institute, Seoul National University Medical Research Center, Seoul, Korea (S.S., C.K.C.); Clinical Research Institute, Seoul National University Hospital, Seoul, Korea (S.S., C.K.C.); Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, Korea (C.K.C.); Department of Nursing, College of Medicine, Chosun University, Gwangju, Korea (J.K.); National Evidence-based Healthcare Collaborating Agency, Seoul, Korea (N.-R.L., E.P.); Department of Neurosurgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science, Seoul, Korea (U.-K.C.); Department of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Inje University, Gimhae, Korea (M.J.S.); Department of Radiation Oncology, St. Vincent's Hospital, School of Medicine, The Catholic University of Korea, Suwon, Korea (S.H.K.).
Neurooncol Pract. 2015 Jun;2(2):93-100. doi: 10.1093/nop/npv006. Epub 2015 May 5.
The aim of this nationwide study was to describe the incidence and health care utilization of adult Korean patients with primary malignant, primary nonmalignant, and metastatic spine tumors between 2009 and 2012.
Patients with primary and metastatic spine tumors were identified from the Korean Health Insurance Review and Assessment Service database between January 1, 2009, and December 31, 2012. Demographics, incidence rate, annual medical cost, and annual hospital stay of each new patient were reviewed.
Of 1600 primary spine tumors diagnosed from 2009 to 2012, 373 (23.3%) were malignant, and 1227 (76.7%) were nonmalignant. The most common tumor type was neoplasm of spinal cord among primary malignant (C72.0, 51.5%) and primary nonmalignant (D33.4, 66.2%) spine tumors. Differences in primary malignant, primary nonmalignant, and metastatic spine tumor incidence by sex were significant ( = .004, <.001, and <.001, respectively). The annual incidence rate of primary nonmalignant and metastatic spine tumors increased significantly over the study period ( = .005 and <.001, respectively). Lung, liver/biliary, and breast were the most prevalent original tumor sites for metastatic spine tumors. In 2011, average annual medical costs associated with treatment of primary malignant, primary nonmalignant, and metastatic tumors were US $15 223, $6502, and $16 038, respectively. Average annual hospital stay durations for primary malignant, primary nonmalignant, and metastatic spine tumors in 2011 were 103.4, 61.7, and 79.6 days, respectively.
This is the first nationwide analysis of spine tumors, including metastatic spine tumors, in Asia.
这项全国性研究的目的是描述2009年至2012年间韩国成年原发性恶性、原发性非恶性和转移性脊柱肿瘤患者的发病率及医疗保健利用情况。
从韩国健康保险审查与评估服务数据库中识别出2009年1月1日至2012年12月31日期间患有原发性和转移性脊柱肿瘤的患者。对每位新患者的人口统计学信息、发病率、年度医疗费用和年度住院时间进行了审查。
在2009年至2012年诊断出的1600例原发性脊柱肿瘤中，373例（23.3%）为恶性，1227例（76.7%）为非恶性。在原发性恶性（C72.0，51.5%）和原发性非恶性（D33.4，66.2%）脊柱肿瘤中，最常见的肿瘤类型是脊髓肿瘤。原发性恶性、原发性非恶性和转移性脊柱肿瘤发病率的性别差异具有显著性（分别为P = 0.004、P < 0.001和P < 0.001）。在研究期间，原发性非恶性和转移性脊柱肿瘤的年发病率显著上升（分别为P = 0.005和P < 0.001）。肺、肝/胆和乳腺是转移性脊柱肿瘤最常见的原发肿瘤部位。2011年，原发性恶性、原发性非恶性和转移性肿瘤治疗的年均医疗费用分别为15223美元、6502美元和16038美元。2011年，原发性恶性、原发性非恶性和转移性脊柱肿瘤的年均住院时间分别为103.4天、61.7天和79.6天。
这是亚洲首次对包括转移性脊柱肿瘤在内的脊柱肿瘤进行全国性分析。
