O'Shaughnessy Kevin M, Karet Fiona E
Clinical Pharmacology Unit, University of Cambridge, UK.
J Clin Invest. 2004 Apr;113(8):1075-81. doi: 10.1172/JCI21560.
The kidney plays a central role in our ability to maintain appropriate sodium balance, which is critical to determination of blood pressure. In this review we outline current knowledge of renal salt handling at the molecular level, and, given that Westernized societies consume more salt than is required for normal physiology, we examine evidence that the lowering of salt intake can combat hypertension.
肾脏在我们维持适当钠平衡的能力中起着核心作用，而钠平衡对于血压的测定至关重要。在本综述中，我们概述了目前在分子水平上对肾脏盐处理的认识，并且鉴于西方化社会摄入的盐超过了正常生理所需，我们研究了减少盐摄入量可对抗高血压的证据。
