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次氯酸钠和臭氧对模拟绞窄性结直肠癌梗阻肠吻合口愈合的影响。

Effects of sodium hypochlorite and ozone on healing of intestinal anastomosis in simulated strangulation colorectal obstruction.

作者信息

Lelyanov A D, Sergienko V I, Ivliev N V, Emel'yanov V V, Guseva E D

机构信息

Smolensk State Medical Academy.

出版信息

Bull Exp Biol Med. 2004 Jan;137(1):103-5. doi: 10.1023/b:bebm.0000024399.34545.cd.

DOI:10.1023/b:bebm.0000024399.34545.cd
PMID:15085259
Abstract

Strangulation colorectal obstruction was modeled in 60 Wistar rats. Necrotic segment of the intestine was resected under conditions of peritonitis and end-to-end intestinal anastomosis was performed on a PCV catheter conducted through the anus. Sodium hypochlorite and ozone solution were used for sanitation of the abdominal cavity and intestinal lavage, and the intestinal anastomosis was coated with Ozonide (ozonized oil). The use of physicochemical methods notably reduced the incidence of postoperative pyoinflammatory complications, incompetence of intestinal anastomosis sutures, and animal mortality.

摘要

在60只Wistar大鼠中建立绞窄性大肠梗阻模型。在腹膜炎条件下切除坏死肠段,并通过经肛门插入的PCV导管进行端端肠吻合术。使用次氯酸钠和臭氧溶液进行腹腔清洁和肠道灌洗,肠吻合口用臭氧油(臭氧化油)覆盖。使用物理化学方法显著降低了术后脓性炎症并发症的发生率、肠吻合缝线不愈合的发生率以及动物死亡率。

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