Kurihara K, Sanada E, Yasuda S, Yamasaki H
Department of Pathology, Uwajima City Hospital, Japan.
Oral Surg Oral Med Oral Pathol. 1992 Aug;74(2):201-5. doi: 10.1016/0030-4220(92)90383-2.
A case of desmoplastic melanoma in a 58-year-old man is reported. This rare malignancy occurred in the maxillary alveolus, appearing as an epulis. Histologically, the tumor was flanked by melanocytic proliferation in the adjacent mucosae. At the time of local recurrence after partial maxillectomy, the tumor showed a polypoid growth, with an increase in cellularity and mitotic rate resembling spindle cell carcinoma. The value of immunostaining for diagnosis is stressed.
报告了一例58岁男性促结缔组织增生性黑素瘤。这种罕见的恶性肿瘤发生在上颌牙槽，表现为龈瘤。组织学上，肿瘤两侧的相邻黏膜有黑素细胞增生。部分上颌骨切除术后局部复发时，肿瘤呈息肉样生长，细胞增多，有丝分裂率增加，类似梭形细胞癌。强调了免疫染色在诊断中的价值。
