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一名患有巨大骶尾部畸胎瘤的婴儿的自体脐带血输血

Autologous cord blood transfusion in an infant with a huge sacrococcygeal teratoma.

作者信息

Hosono Shigeharu, Mugishima Hideo, Nakano Yuko, Murabayashi Masao, Shimada Masami, Minato Michiyoshi, Takahashi Shigeru, Harada Kensuke, Ikeda Taro, Fukuzawa Masahiro

机构信息

Department of Pediatrics, Nihon University School of Medicine, Tokyo, Japan.

出版信息

J Perinat Med. 2004;32(2):187-9. doi: 10.1515/JPM.2004.035.

Abstract

We describe a case of cord blood harvest for autologous transfusion in a neonate weighing 3,992 g with a giant sacrococcygeal teratoma. The umbilical vein was pierced with an 18-gauge needle, and placental blood was withdrawn into two 50-ml syringes filled with 4 ml of citrate-phosphate-dextrose solution. Resection of the sacrococcygeal teratoma was performed on day one. During the operation the infant lost 46 ml of whole blood, more than 15% of the estimated total blood volume, and thus underwent autologous transfusion with 27.8 ml of packed red cells obtained from autologous cord blood. Consequently, she could avoid homologous blood transfusion during the hospital stay. This case highlights the safety of this procedure, with no evidence of consumption coagulopathy, hemolysis or bacterial infection.

摘要

我们描述了一例为一名体重3992克、患有巨大骶尾部畸胎瘤的新生儿采集脐带血用于自体输血的病例。用18号针头穿刺脐静脉,将胎盘血抽入两个装有4毫升枸橼酸盐 - 磷酸盐 - 葡萄糖溶液的50毫升注射器中。在出生第一天进行了骶尾部畸胎瘤切除术。手术过程中,婴儿失血量为46毫升全血,超过估计总血容量的15%,因此接受了从自体脐带血中获得的27.8毫升浓缩红细胞的自体输血。因此,她在住院期间避免了异体输血。该病例突出了此程序的安全性,没有消耗性凝血病、溶血或细菌感染的迹象。

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