Karatzas G, Kouskos E, Kouraklis G, Mantas D, Papachristodoulou A
Second Department of Propedeutic Surgery, Athens University Medical School, Laiko General Hospital, Athens, Greece.
Int Surg. 2004 Jan-Mar;89(1):21-6.
Gastrointestinal (GI) carcinoids are rare neuroendocrine tumors of great interest because of the multitude of the peptide hormones they produce, their clinical manifestations, the carcinoid syndrome they cause, their biologic behavior, and the methods of their surgical and adjuvant treatment. In this retrospective study, 25 patients with carcinoid tumors admitted and surgically treated in our department during the last 10 years are presented. Most of the cases were located in the ileum (n = 8) and appendix (n = 12). The remaining cases were located in the rectum (n = 2), stomach (n = 1), duodenum (n = 1), and ileocecal valve (n = 1). After tumor resection and postoperative treatment, mainly with somatostatin analogs, our patients had a good recovery, and only five deaths were reported during follow-up. Carcinoids, despite the fact that they are usually silent and diagnosed with advanced stage, have good prognosis and offer, after effective treatment, long survival.
胃肠道类癌是一种罕见的神经内分泌肿瘤，因其产生的多种肽类激素、临床表现、所引发的类癌综合征、生物学行为以及手术和辅助治疗方法而备受关注。在这项回顾性研究中，我们呈现了过去10年在我院收治并接受手术治疗的25例类癌肿瘤患者。大多数病例位于回肠（n = 8）和阑尾（n = 12）。其余病例分别位于直肠（n = 2）、胃（n = 1）、十二指肠（n = 1）和回盲瓣（n = 1）。在肿瘤切除及术后主要采用生长抑素类似物治疗后，我们的患者恢复良好，随访期间仅报告了5例死亡病例。类癌尽管通常无症状且多在晚期被诊断出来，但预后良好，经过有效治疗后可实现长期生存。
